New combo therapy fights back against stubborn blood cancers

NCT ID NCT05583149

Summary

This study is testing if adding the drug acalabrutinib to a personalized cell therapy (liso-cel) is safe and effective for adults with aggressive B-cell lymphomas that have come back or not responded to at least two prior treatments. Participants receive a one-time infusion of the cell therapy and take the drug orally for up to a year, with long-term follow-up. The goal is to see if this combination can better control the cancer.

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Contacts and locations

Locations

  • Beth-Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.