Cancer trial pits two antibody weapons against lymphoma

NCT ID NCT00006721

Completed Disease control Sponsor: SWOG Cancer Research Network Source: ClinicalTrials.gov ↗

Summary

This large, completed study aimed to find the better add-on treatment for newly diagnosed follicular lymphoma, a type of blood cancer. It compared standard chemotherapy (CHOP) combined with one of two different antibody drugs: rituximab or a radioactive antibody called tositumomab. The goal was to see which combination helped patients live longer without their cancer getting worse and had fewer side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Study site

Great Falls, Montana, 59405, United States
Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
Adventist Medical Center

Portland, Oregon, 97216, United States
Alaska Regional Hospital Cancer Center

Anchorage, Alaska, 99508, United States
Allenmore Hospital

Tacoma, Washington, 98405, United States
Alta Bates Summit Comprehensive Cancer Center

Berkeley, California, 94704, United States
Alvin and Lois Lapidus Cancer Institute at Sinai Hospital

Baltimore, Maryland, 21215, United States
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
Associates in Womens Health, PA - North Review

Wichita, Kansas, 67208, United States
Barbara Ann Karmanos Cancer Institute

Detroit, Michigan, 48201-1379, United States
Battle Creek Health System Cancer Care Center

Battle Creek, Michigan, 49017, United States
Bay Regional Medical Center

Bay City, Michigan, 48708, United States
Berkshire Hematology Oncology, PC

Pittsfield, Massachusetts, 01201, United States
Big Sky Oncology

Great Falls, Montana, 59405-5309, United States
Billings Clinic - Downtown

Billings, Montana, 59107-7000, United States
Blanchard Valley Medical Associates

Findlay, Ohio, 45840, United States
Borgess Medical Center

Kalamazoo, Michigan, 49001, United States
Bozeman Deaconess Cancer Center

Bozeman, Montana, 59715, United States
BroMenn Regional Medical Center

Normal, Illinois, 61761, United States
Bronson Methodist Hospital

Kalamazoo, Michigan, 49007, United States
Butterworth Hospital at Spectrum Health

Grand Rapids, Michigan, 49503, United States
CCOP - Atlanta Regional

Atlanta, Georgia, 30342, United States
CCOP - Cancer Research for the Ozarks

Springfield, Missouri, 65802, United States
CCOP - Carle Cancer Center

Urbana, Illinois, 61801, United States
CCOP - Columbia River Oncology Program

Portland, Oregon, 97225, United States
CCOP - Columbus

Columbus, Ohio, 43215, United States
CCOP - Dayton

Dayton, Ohio, 45429, United States
CCOP - Grand Rapids

Grand Rapids, Michigan, 49503, United States
CCOP - Greenville

Greenville, South Carolina, 29615, United States
CCOP - Illinois Oncology Research Association

Peoria, Illinois, 61615, United States
CCOP - Kansas City

Kansas City, Missouri, 64131, United States
CCOP - Montana Cancer Consortium

Billings, Montana, 59101, United States
CCOP - Northern Indiana CR Consortium

South Bend, Indiana, 46601, United States
CCOP - Northwest

Tacoma, Washington, 98405, United States
CCOP - St. Louis-Cape Girardeau

St Louis, Missouri, 63141, United States
CCOP - Virginia Mason Research Center

Seattle, Washington, 98101, United States
CCOP - Wichita

Wichita, Kansas, 67214, United States
California Pacific Medical Center - California Campus

San Francisco, California, 94118, United States
Cancer Care Northwest - Spokane South

Spokane, Washington, 99202, United States
Cancer Center of Kansas, PA - Chanute

Chanute, Kansas, 66720, United States
Cancer Center of Kansas, PA - Dodge City

Dodge City, Kansas, 67801, United States
Cancer Center of Kansas, PA - El Dorado

El Dorado, Kansas, 67042, United States
Cancer Center of Kansas, PA - Kingman

Kingman, Kansas, 67068, United States
Cancer Center of Kansas, PA - Medical Arts Tower

Wichita, Kansas, 67208, United States
Cancer Center of Kansas, PA - Newton

Newton, Kansas, 67114, United States
Cancer Center of Kansas, PA - Parsons

Parsons, Kansas, 67357, United States
Cancer Center of Kansas, PA - Pratt

Pratt, Kansas, 67124, United States
Cancer Center of Kansas, PA - Salina

Salina, Kansas, 67042, United States
Cancer Center of Kansas, PA - Wellington

Wellington, Kansas, 67152, United States
Cancer Center of Kansas, PA - Wichita

Wichita, Kansas, 67214, United States
Cancer Center of Kansas, PA - Winfield

Winfield, Kansas, 67156, United States
Cancer Center of Kansas-Independence

Independence, Kansas, 67301, United States
Cancer Treatment Center at Pekin Hospital

Pekin, Illinois, 61554, United States
Cardinal Bernardin Cancer Center at Loyola University Medical Center

Maywood, Illinois, 60153, United States
Carle Cancer Center at Carle Foundation Hospital

Urbana, Illinois, 61801, United States
Cascade Cancer Center at Evergreen Hospital Medical Center

Kirkland, Washington, 98033, United States
Center for Cancer Care and Research at Watson Clinic, LLP

Lakeland, Florida, 33805, United States
Center for Cancer Therapy at LaPorte Hospital and Health Services

La Porte, Indiana, 46350, United States
Charles B. Eberhart Cancer Center at DeKalb Medical Center

Decatur, Georgia, 30033, United States
Charles F. Kettering Memorial Hospital

Kettering, Ohio, 45429, United States
Charles M. Barrett Cancer Center at University Hospital

Cincinnati, Ohio, 45267, United States
Cleveland Clinic - Wooster

Wooster, Ohio, 44691, United States
Cleveland Clinic Cancer Center at Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Taussig Cancer Center

Cleveland, Ohio, 44195, United States
Clinton Memorial Hospital

Wilmington, Ohio, 45177, United States
Columbia Basin Hematology

Kennewick, Washington, 99336, United States
Community Cancer Center

Normal, Illinois, 61761, United States
Community Hospital of Ottawa

Ottawa, Illinois, 61350, United States
Community Hospital of Springfield and Clark County

Springfield, Ohio, 45505, United States
Community Medical Center

Missoula, Montana, 59801, United States
Community Oncology Group at Cleveland Clinic Cancer Center

Independence, Ohio, 44131, United States
Cotton-O'Neil Cancer Center

Topeka, Kansas, 66606, United States
David C. Pratt Cancer Center at St. John's Mercy

St Louis, Missouri, 63141, United States
David L. Rike Cancer Center at Miami Valley Hospital

Dayton, Ohio, 45409, United States
Decatur Memorial Hospital Cancer Care Institute

Decatur, Illinois, 62526, United States
Desert Regional Medical Center Comprehensive Cancer Center

Palm Springs, California, 92262, United States
Doctors Hospital at Ohio Health

Columbus, Ohio, 43228, United States
Duke Comprehensive Cancer Center

Durham, North Carolina, 27710, United States
Dwight David Eisenhower Army Medical Center

Fort Gordon, Georgia, 30905-5650, United States
Edward Hospital Cancer Center

Naperville, Illinois, 60540, United States
Elkhart General Hospital

Elkhart, Indiana, 46515, United States
Ellis Fischel Cancer Center at University of Missouri - Columbia

Columbia, Missouri, 65203, United States
Eureka Community Hospital

Eureka, Illinois, 61530, United States
Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital

Fairbanks, Alaska, 99701, United States
Fairfield Medical Center

Lancaster, Ohio, 43130, United States
Franciscan Cancer Center at St. Joseph Medical Center

Tacoma, Washington, 98405-3004, United States
Fred Hutchinson Cancer Research Center

Seattle, Washington, 98104, United States
Freeman Cancer Institute at Freeman Health System

Joplin, Missouri, 64804, United States
Galesburg Clinic, PC

Galesburg, Illinois, 61401, United States
Galesburg Cottage Hospital

Galesburg, Illinois, 61401, United States
Genesis - Good Samaritan Hospital

Zanesville, Ohio, 43701, United States
Glacier Oncology, PLLC

Kalispell, Montana, 59901, United States
Good Samaritan Cancer Center

Puyallup, Washington, 98372, United States
Good Samaritan Cancer Center at Good Samaritan Hospital

Kearney, Nebraska, 68848-1990, United States
Good Samaritan Hospital

Dayton, Ohio, 45406, United States
Good Samaritan Hospital Cancer Treatment Center

Cincinnati, Ohio, 45220, United States
Good Samaritan Regional Health Center

Mount Vernon, Illinois, 62864, United States
Grady Memorial Hospital

Delaware, Ohio, 43015, United States
Graham Hospital

Canton, Illinois, 61520, United States
Grandview Hospital

Dayton, Ohio, 45405, United States
Grant Medical Center Cancer Care

Columbus, Ohio, 43215, United States
Great Falls Clinic - Main Facility

Great Falls, Montana, 59405, United States
Greenebaum Cancer Center at University of Maryland Medical Center

Baltimore, Maryland, 21201, United States
Group Health Central Hospital

Seattle, Washington, 98112, United States
Guardian Oncology and Center for Wellness

Missoula, Montana, 59804, United States
Gwinnett Medical Center

Lawrenceville, Georgia, 30045, United States
Hackley Hospital

Muskegon, Michigan, 49442, United States
Harborview Medical Center

Seattle, Washington, 98104, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Helen and Harry Gray Cancer Center at Hartford Hospital

Hartford, Connecticut, 06102-5037, United States
Hematology-Oncology Centers of the Northern Rockies - Billings

Billings, Montana, 59101, United States
Hembree Mercy Cancer Center at St. Edward Mercy Medical Center

Fort Smith, Arkansas, 72903, United States
Holland Community Hospital

Holland, Michigan, 49423, United States
Hollings Cancer Center at Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Hopedale Medical Complex

Hopedale, Illinois, 61747, United States
Howard Community Hospital

Kokomo, Indiana, 46904, United States
Hulston Cancer Center at Cox Medical Center South

Springfield, Missouri, 65807, United States
Huntsman Cancer Institute at University of Utah

Salt Lake City, Utah, 84112, United States
Illinois Valley Community Hospital

Peru, Illinois, 61354, United States
Independence Regional Health Center

Independence, Missouri, 64050, United States
James P. Wilmot Cancer Center at University of Rochester Medical Center

Rochester, New York, 14642, United States
Joe Arrington Cancer Research and Treatment Center

Lubbock, Texas, 79410-1894, United States
Johnson County Radiation Therapy

Overland Park, Kansas, 66210, United States
Joliet Oncology-Hematology Associates, Limited - West

Joliet, Illinois, 60435, United States
Josephine Ford Cancer Center at Henry Ford Hospital

Detroit, Michigan, 48202, United States
Kalispell Medical Oncology at KRMC

Kalispell, Montana, 59901, United States
Kalispell Regional Medical Center

Kalispell, Montana, 59901, United States
Kansas City Cancer Center at St. Joseph's Medical Mall

Kansas City, Missouri, 64114, United States
Kennestone Cancer Center at Wellstar Kennestone Hospital

Marietta, Georgia, 30060, United States
Lacks Cancer Center at Saint Mary's Health Care

Grand Rapids, Michigan, 49503, United States
Lahey Clinic Medical Center - Burlington

Burlington, Massachusetts, 01805, United States
Lakeland Regional Cancer Care Center - St. Joseph

Saint Joseph, Michigan, 49085, United States
Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States
Legacy Emanuel Hospital and Health Center and Children's Hospital

Portland, Oregon, 97227, United States
Legacy Good Samaritan Hospital & Comprehensive Cancer Center

Portland, Oregon, 97210, United States
Legacy Meridian Park Hospital

Tualatin, Oregon, 97062, United States
Legacy Mount Hood Medical Center

Gresham, Oregon, 97030, United States
Licking Memorial Cancer Care Program at Licking Memorial Hospital

Newark, Ohio, 43055, United States
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill

Chapel Hill, North Carolina, 27599-7295, United States
Lombardi Comprehensive Cancer Center at Georgetown University Medical Center

Washington D.C., District of Columbia, 20007, United States
Lynchburg Hematology-Oncology Clinic

Lynchburg, Virginia, 24501, United States
Marin Cancer Institute at Marin General Hospital

Greenbrae, California, 94904, United States
Mary Rutan Hospital

Bellefontaine, Ohio, 43311, United States
Mason District Hospital

Havana, Illinois, 62644, United States
McDonough District Hospital

Macomb, Illinois, 61455, United States
McDowell Cancer Center at Akron General Medical Center

Akron, Ohio, 44307, United States
Mecosta County Medical Center

Big Rapids, Michigan, 49307, United States
Memorial Hospital

Carthage, Illinois, 62321, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Menorah Medical Center

Overland Park, Kansas, 66209, United States
Mercy Medical Center

Springfield, Ohio, 45504, United States
Mercy Medical Center - Sioux City

Sioux City, Iowa, 51104, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Metro Health Hospital

Wyoming, Michigan, 49519, United States
Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Midwest Hematology Oncology Group, Incorporated

St Louis, Missouri, 63109, United States
Minor and James Medical, PLLC

Seattle, Washington, 98104, United States
Montana Cancer Center at St. Patrick Hospital and Health Sciences Center

Missoula, Montana, 59807, United States
Montana Cancer Specialists at Montana Cancer Center

Missoula, Montana, 59807-7877, United States
Mount Carmel Health - West Hospital

Columbus, Ohio, 43222, United States
Mount Carmel St. Ann's Cancer Center

Westerville, Ohio, 43081, United States
Mountain States Tumor Institute at St. Luke's Regional Medical Center

Boise, Idaho, 83712, United States
MultiCare Regional Cancer Center at Tacoma General Hospital

Tacoma, Washington, 98405, United States
Munson Medical Center

Traverse City, Michigan, 49684, United States
New York Weill Cornell Cancer Center at Cornell University

New York, New York, 10021, United States
North Kansas City Hospital

Kansas City, Missouri, 64116, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital

Yakima, Washington, 98902, United States
Northeast Georgia Medical Center

Gainesville, Georgia, 30501, United States
Northern Rockies Radiation Oncology Center

Billings, Montana, 59101, United States
Northside Hospital Cancer Center

Atlanta, Georgia, 30342-1611, United States
OSF St. Francis Medical Center

Peoria, Illinois, 61637, United States
Olympic Hematology and Oncology

Bremerton, Washington, 98310, United States
Olympic Medical Center

Port Angeles, Washington, 98362, United States
Oncology Care Associates, PLLC

Saint Joseph, Michigan, 49085, United States
Oncology Hematology Associates of Central Illinois, PC - Ottawa

Ottawa, Illinois, 61350, United States
Oncology Hematology Associates of Central Illinois, PC - Peoria

Peoria, Illinois, 61615, United States
Palmetto Health South Carolina Cancer Center

Columbia, South Carolina, 29203, United States
Parvin Radiation Oncology

Kansas City, Missouri, 64116, United States
Pearlman Comprehensive Cancer Center at South Georgia Medical Center

Valdosta, Georgia, 31603, United States
Peninsula Medical Center

Burlingame, California, 94010, United States
Perry Memorial Hospital

Princeton, Illinois, 61356, United States
Piedmont Hospital

Atlanta, Georgia, 30309, United States
Polyclinic First Hill

Seattle, Washington, 98122, United States
Proctor Hospital

Peoria, Illinois, 61614, United States
Providence Cancer Center at Providence Portland Medical Center

Portland, Oregon, 97213-2967, United States
Providence Medical Center

Kansas City, Kansas, 66112, United States
Providence Milwaukie Hospital

Milwaukie, Oregon, 97222, United States
Providence St. Vincent Medical Center

Portland, Oregon, 97225, United States
Radiation Oncology Associates of Kansas City at Northland Radiation Oncology Center

Kansas City, Missouri, 64154, United States
Regional Cancer Center at Memorial Medical Center

Springfield, Illinois, 62781-0001, United States
Reid Hospital & Health Care Services

Richmond, Indiana, 47374, United States
Riverside Methodist Hospital Cancer Care

Columbus, Ohio, 43214-3998, United States
Roper St. Francis Cancer Center at Roper Hospital

Charleston, South Carolina, 29401, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263-0001, United States
Rush-Copley Cancer Care Center

Aurora, Illinois, 60504, United States
Ruth G. McMillan Cancer Center at Greene Memorial Hospital

Xenia, Ohio, 45385, United States
Sacred Heart Cancer Center at Sacred Heart Hospital

Pensacola, Florida, 32504, United States
Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

Boise, Idaho, 83706, United States
Saint Anthony Memorial Health Centers

Michigan City, Indiana, 46360, United States
Saint Anthony's Hospital at Saint Anthony's Health Center

Alton, Illinois, 62002, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint Joseph Regional Medical Center

South Bend, Indiana, 46617, United States
Saint Joseph's Hospital of Atlanta

Atlanta, Georgia, 30342-1701, United States
Saint Luke's Cancer Institute at Saint Luke's Hospital

Kansas City, Missouri, 64111, United States
Saint Luke's Hospital

Chesterfield, Missouri, 63017, United States
Samaritan North Cancer Care Center

Dayton, Ohio, 45415, United States
Schiffler Cancer Center at Wheeling Hospital

Wheeling, West Virginia, 26003, United States
Shawnee Mission Medical Center

Shawnee Mission, Kansas, 66204, United States
Siouxland Hematology-Oncology Associates, LLP

Sioux City, Iowa, 51101, United States
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

St Louis, Missouri, 63110, United States
Sletten Cancer Institute at Benefis Healthcare

Great Falls, Montana, 59405, United States
Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital

Gape Girardeau, Missouri, 63701, United States
Southern Regional Medical Center

Riverdale, Georgia, 30274-2600, United States
Southwest Medical Center

Liberal, Kansas, 67901, United States
Southwest Washington Medical Center Cancer Center

Vancouver, Washington, 98668, United States
St. Clare Hospital

Tacoma, Washington, 98499, United States
St. Francis Hospital

Federal Way, Washington, 98003, United States
St. Francis Hospital and Health Centers - Beech Grove Campus

Beech Grove, Indiana, 46107, United States
St. James Healthcare Cancer Care

Butte, Montana, 59701, United States
St. John's Regional Health Center

Springfield, Missouri, 65804, United States
St. John's Regional Medical Center

Joplin, Missouri, 64804, United States
St. Joseph Cancer Center

Bellingham, Washington, 98225, United States
St. Joseph Medical Center

Bloomington, Illinois, 61701, United States
St. Joseph Medical Center

Kansas City, Missouri, 64114, United States
St. Luke's Regional Medical Center

Sioux City, Iowa, 51104, United States
St. Margaret's Hospital

Spring Valley, Illinois, 61362, United States
St. Peter's Hospital

Helena, Montana, 59601, United States
St. Rita's Medical Center

Lima, Ohio, 45801, United States
St. Vincent Healthcare Cancer Care Services

Billings, Montana, 59101, United States
Stanford Cancer Center

Stanford, California, 94305-5824, United States
Strecker Cancer Center at Marietta Memorial Hospital

Marietta, Ohio, 45750, United States
Sutter Health - Western Division Cancer Research Group

Greenbrae, California, 94904, United States
Sutter Solano Medical Center

Vallejo, California, 94589, United States
Swedish Cancer Institute at Swedish Medical Center - First Hill Campus

Seattle, Washington, 98122-4307, United States
Tammy Walker Cancer Center at Salina Regional Health Center

Salina, Kansas, 67401, United States
Tripler Army Medical Center

Honolulu, Hawaii, 96859, United States
Truman Medical Center - Hospital Hill

Kansas City, Missouri, 64108, United States
Tucker Center for Cancer Care at Orange Regional Medical Center

Middletown, New York, 10940-4199, United States
UMC Southwest Cancer and Research Center

Lubbock, Texas, 79415-3364, United States
UNMC Eppley Cancer Center at the University of Nebraska Medical Center

Omaha, Nebraska, 68198-6805, United States
UVMC Cancer Care Center at Upper Valley Medical Center

Troy, Ohio, 45373-1300, United States
University Cancer Center at University of Washington Medical Center

Seattle, Washington, 98195-6043, United States
University of California Davis Cancer Center

Sacramento, California, 95817, United States
University of Chicago Cancer Research Center

Chicago, Illinois, 60637-1470, United States
University of Illinois Cancer Center

Chicago, Illinois, 60612-7243, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109-0942, United States
University of Mississippi Cancer Clinic

Jackson, Mississippi, 39216, United States
Valley Medical Center

Renton, Washington, 98055, United States
Veterans Affairs Medical Center - Columbia (Truman Memorial)

Columbia, Missouri, 65201, United States
Veterans Affairs Medical Center - Dayton

Dayton, Ohio, 45428, United States
Veterans Affairs Medical Center - Hines

Hines, Illinois, 60141, United States
Via Christi Cancer Center at Via Christi Regional Medical Center

Wichita, Kansas, 67214, United States
Wayne Memorial Hospital, Incorporated

Goldsboro, North Carolina, 27534, United States
Welch Cancer Center at Sheridan Memorial Hospital

Sheridan, Wyoming, 82801, United States
WellStar Cobb Hospital

Austell, Georgia, 30106, United States
Wenatchee Valley Medical Center

Wenatchee, Washington, 98801-2028, United States
Wesley Medical Center

Wichita, Kansas, 67214, United States
West Florida Cancer Institute at West Florida Hospital - Pensacola

Pensacola, Florida, 32514, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007-3731, United States

Conditions

Explore the condition pages connected to this study.

LYMPHOMA