New cancer drug trial targets specific genetic weakness

NCT ID NCT06561685

Summary

This study is testing a new drug called LY4050784 for people with advanced solid tumors that have a specific genetic change called a SMARCA4/BRG1 alteration. The main goals are to find a safe dose of the drug, given alone or with other cancer treatments, and to see if it helps shrink or control the cancer. The study is open to adults with certain advanced cancers, including lung cancer, who have few or no other standard treatment options.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aichi Cancer Center Hospital

    RECRUITING

    Nagoya, 464-8681, Japan

  • Charite-Universitatsmedizin Berlin

    NOT_YET_RECRUITING

    Berlin, 10117, Germany

  • Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Florida Cancer Specialists ORLANDO/DDU

    RECRUITING

    Lake Mary, Florida, 32746, United States

  • Hospital Universitari Vall d'Hebron

    NOT_YET_RECRUITING

    Barcelona, 08035, Spain

  • Institut Bergonie

    NOT_YET_RECRUITING

    Bordeaux, 33 076, France

  • Institut Curie

    RECRUITING

    Paris, 75248, France

  • Institut Gustave Roussy-Gustave Roussy Cancer Center -DITEP

    NOT_YET_RECRUITING

    Villejuif, 94800, France

  • Krankenhaus Nordwest

    NOT_YET_RECRUITING

    Frankfurt am Main, 60488, Germany

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030-4009, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • National Cancer Center

    NOT_YET_RECRUITING

    Ilsandong-gu, 10408, South Korea

  • National Cancer Center Hospital

    RECRUITING

    Chūōku, 104-0045, Japan

  • National Cancer Center Hospital East

    RECRUITING

    Kashiwa, 277-8577, Japan

  • Ohio State University Hospital

    RECRUITING

    Columbus, Ohio, 43210, United States

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute at HealthOne

    RECRUITING

    Denver, Colorado, 80218, United States

  • Severance Hospital, Yonsei University Health System

    NOT_YET_RECRUITING

    Seoul, 03722, South Korea

  • Shizuoka Cancer Center

    RECRUITING

    Nagaizumi-cho,Sunto-gun, 411-8777, Japan

  • South Texas Accelerated Research Therapeutics (START) Madrid - Hospital Fundacion Jimenez Diaz

    NOT_YET_RECRUITING

    Madrid, 28040, Spain

  • The Cancer Institute Hospital of JFCR

    RECRUITING

    Kōtō City, 135-8550, Japan

  • The Catholic University of Korea, St. Vincent's Hospital

    NOT_YET_RECRUITING

    Suwon, 16247, South Korea

  • UCLA

    NOT_YET_RECRUITING

    Santa Monica, California, 90404, United States

  • USO-Virginia Cancer Specialists, PC

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Universitaetsklinikum Essen

    NOT_YET_RECRUITING

    Essen, 45147, Germany

  • University of Chicago

    RECRUITING

    New Lenox, Illinois, 60451, United States

  • University of Colorado Health Hospital

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

  • Vanderbilt-Ingram Cancer Center

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37232-6307, United States

Conditions

Explore the condition pages connected to this study.