One-Shot gene therapy aims to free patients from monthly eye injections

NCT ID NCT07317934

Summary

This large, late-stage trial is testing whether a single gene therapy injection into the eye (called LX102) can work as well as or better than the standard monthly eye injections for wet age-related macular degeneration. The main goal is to see if the one-time treatment can improve or maintain vision over a year and reduce the need for repeated injections. It is for adults aged 50-80 who have already shown improvement with standard treatments.

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Contacts and locations

Locations

  • Aier Eye Hospital Group Co., LTD. Changsha Aier Eye Hospital

    NOT_YET_RECRUITING

    Changsha, Hunan, 410015, China

  • Beijing Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100730, China

  • Central Theater Command General Hospital of PLA

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430060, China

  • Eye & ENT Hospital of Fudan University

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200031, China

  • Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong

    NOT_YET_RECRUITING

    Shantou, Guangdong, 515041, China

  • Peking Union Medical College Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100730, China

  • Qilu Hospital of Shandong University

    NOT_YET_RECRUITING

    Jinan, Shandong, 250012, China

  • Qingdao Eye Hospital Affiliated to Shandong First Medical University

    NOT_YET_RECRUITING

    Qingdao, Shandong, 266071, China

  • Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 201801, China

  • Shandong Eye Hospital

    NOT_YET_RECRUITING

    Jinan, Shandong, 250021, China

  • Shanghai General Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200080, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanxi Bethune Hospital

    NOT_YET_RECRUITING

    Taiyuan, Shanxi, 030032, China

  • Shanxi Eye Hospital

    NOT_YET_RECRUITING

    Taiyuan, Shanxi, 030002, China

  • Sichuan Provincial People's Hospital

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 646100, China

  • The Affiliated Eye Hospital of Nanjing Medical University

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, 210029, China

  • The Eye Hospital of Wenzhou Medical University

    NOT_YET_RECRUITING

    Wenzhou, Zhejiang, 325027, China

  • The First Affiliated Hospital of Air Force Medical University

    NOT_YET_RECRUITING

    Xi’an, Shanxi, 710032, China

  • The First Affiliated Hospital of Jinan University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510632, China

  • The First Affiliated Hospital of University of Science and Technology of China

    NOT_YET_RECRUITING

    Hefei, Anhui, 230601, China

  • The Second Affiliated Hospital of Chongqing Medical University

    NOT_YET_RECRUITING

    Chongqing, Chongqing Municipality, 400010, China

  • The Second Affiliated Hospital of Harbin Medical University

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150001, China

  • The Second Hospital of Jilin University

    NOT_YET_RECRUITING

    Changchun, Jilin, 130022, China

  • The Second Xiangya Hospital, Central South University

    NOT_YET_RECRUITING

    Changsha, Hunan, 410011, China

  • Tianjin Eye Hospital

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

  • Tianjin Medical University Eye Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300384, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital, Sichuan University

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 610041, China

  • Xi 'an People's Hospital (Xi 'an No.4 Hospital)

    NOT_YET_RECRUITING

    Xi’an, Shanxi, 710004, China

  • Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200092, China

  • Xuzhou First People's Hospital

    NOT_YET_RECRUITING

    Xuzhou, Jiangsu, 221002, China

  • Zhejiang Provincial People's Hospital

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310014, China

  • Zhongshan Ophthalmic Center, Sun Yat-sen University

    NOT_YET_RECRUITING

    Zhongshan, Guangdong, 510623, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.