Gene therapy shot aims to tame leading cause of blindness

NCT ID NCT06196840

First seen Mar 13, 2026 · Last updated May 15, 2026 · Updated 9 times

Summary

This study tests a new gene therapy called LX102 for people with wet age-related macular degeneration (nAMD), a common cause of vision loss. About 50 adults aged 50 to 89 who have already responded to standard anti-VEGF injections will receive the treatment. The goal is to see if LX102 is safe and can help maintain or improve vision while reducing the need for frequent eye injections.

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Contacts and locations

Locations

  • Anhui Provincial Hospital

    Hefei, Anhui, China

  • Guangzhou Aier Eye Hospital

    Guangzhou, China

  • Peking Union Medical College Hospital

    Beijing, China

  • Shanghai Eye and ENT Hospital

    Shanghai, China

  • Shanghai General Hospital

    Shanghai, China

  • Shanxi Eye Hospital

    Taiyuan, China

  • Tianjin Medical University Eye Hospital

    Tianjin, China

  • West China Hospital of Sichuan University

    Chengdu, China

  • Xuzhou No.1 People's Hospital

    Xuzhou, China

  • Zhejiang University Eye Hospital

    Hangzhou, Zhejiang, China

  • Zhongshan Ophthalmic Center of Sun Yat-Sen University

    Guangzhou, China

Conditions

Explore the condition pages connected to this study.