Radioactive injection shows promise in slowing neuroendocrine tumor growth
NCT ID NCT05459844
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This Phase 3 study tested a radioactive drug called Lutetium-177 oxodotreotide against a high dose of the standard drug octreotide in 196 people with advanced neuroendocrine tumors that had stopped responding to treatment. The main goal was to see if the radioactive drug could delay tumor growth better than octreotide. Participants received either four injections of the radioactive drug or regular octreotide shots, and their tumors were monitored over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lutetium-177 oxodotreotide injection (a type of radioactive drug)
What this could lead to
If this treatment works, it could offer a more effective option to slow tumor growth in people with advanced neuroendocrine tumors that are no longer controlled by standard therapy.
What could go wrong
This is a Phase 3 trial, but results are not yet published. The radioactive drug may cause side effects like kidney or bone marrow damage, and not all patients may respond.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Affiliated Hospital of Southwest Medical University
Luzhou, Sichuan, 646000, China
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Chinese PLA General Hospital
Beijing, Beijing Municipality, 100853, China
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Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, 200032, China
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Henan Provincial People's Hospital
Zhengzhou, Henan, 450003, China
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Mianyang Central Hospital
Mianyang, Sichuan, 621099, China
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Nanjing First Hospital
Nanjing, Jiangsu, 210006, China
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Qilu Hospital of Shandong University
Jinan, Shandong, 250012, China
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The First Affiliated Hospital of AFMU
Xi'an, Shaanxi, 710032, China
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The First Affiliated Hospital of Jinan University
Guangzhou, Guangdong, 510630, China
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The First Affiliated Hospital of Shanxi Medical University
Taiyuan, Shanxi, 030012, China
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The First Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, 510080, China
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The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, 710061, China
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The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, 361003, China
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The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, 450052, China
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The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310003, China
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The First Afilliated Hospital of Fujian Medical University
Fuzhou, Fujian, 350005, China
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The first hospital of Jilin University
Changchun, Jilin, 130021, China
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Tianjin Medical University Cancer Institute & Hospital
Tianjin, Tianjin Municipality, 300060, China
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Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology
Wuhan, Hubei, 430030, China
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Union Hospital Tongji Medical College Huazhong University of Science and Technology
Wuhan, Hubei, 430022, China
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West China Hospital of Sichuan University
Chengdu, Sichuan, 610041, China
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Zhejiang Cancer Hospital
Hangzhou, Zhejiang, 310022, China
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Zhongshan Hospital, Fudan University
Shanghai, Shanghai Municipality, 200032, China