Radioactive drug lutathera tested in teens with rare cancers

NCT ID NCT04711135

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a radioactive drug called Lutathera in teenagers aged 12 to 17 who have rare tumors of the digestive system or adrenal glands. The goal is to see if the drug is safe and how much radiation reaches organs. Eleven teens are taking part, and researchers are watching for side effects and measuring radiation doses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lutathera (a radioactive drug given by IV)

What this could lead to

If it works, this could provide a new treatment option for teenagers with rare neuroendocrine tumors and related cancers that are hard to treat.

What could go wrong

This is a very small, early-phase study with only 11 participants, so results may not apply to all patients. The drug is radioactive and can cause side effects like kidney or bone marrow damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

digestive system neuroendocrine neoplasm digestive system neuroendocrine tumor, grade 1/2 paraganglioma pheochromocytoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Léon Berard

    Lyon, France

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinnati Children's Hospital

    Cincinnati, Ohio, 45229-3039, United States

  • Hospital Universitari Vall d'Hebron

    Barcelona, Spain

  • Maria Sklodowska-Curie National Research Institute of Oncology

    Gliwice, Poland

  • University College Hospital of London

    London, United Kingdom

  • University of Kentucky

    Lexington, Kentucky, 40536, United States