New shot offers hope to tame rogue immune system in lupus

NCT ID NCT05639114

Ongoing Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether adding a new injectable drug called ianalumab to standard lupus care can better control the disease. About 436 people with active lupus will receive either the real drug or a placebo shot monthly or quarterly for over a year. The main goal is to see if the drug significantly reduces lupus disease activity and allows patients to use lower doses of steroids.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Accurate Clinical Research

League City, Texas, 77573, United States
Accurate Clinical Research Research

Baytown, Texas, 77521, United States
Chicago Clinical Research Inst

Chicago, Illinois, 60607, United States
Clinical Res Of W Florida

Clearwater, Florida, 33765, United States
Clinical Research of West Florida Inc

Tampa, Florida, 33603, United States
Epic Medical Research

Red Oak, Texas, 75154, United States
GNP Research

Cooper City, Florida, 33024, United States
Henry Ford Health

Detroit, Michigan, 48202, United States
Lake Cumberland Rheumatology and In

New Albany, Indiana, 47150, United States
Millennium Clinical Trials

Westlake Village, California, 91361, United States
Novartis Investigative Site

San Miguel, Tucumán Province, T4000CBC, Argentina
Novartis Investigative Site

San Miguel de Tucumán, 4000, Argentina
Novartis Investigative Site

Fortaleza, Ceará, 60125-025, Brazil
Novartis Investigative Site

Vitória, Espírito Santo, 29055 450, Brazil
Novartis Investigative Site

Salvador, Estado de Bahia, 40150 150, Brazil
Novartis Investigative Site

Salvador, Estado de Bahia, 40444 130, Brazil
Novartis Investigative Site

Belo Horizonte, Minas Gerais, 30150-221, Brazil
Novartis Investigative Site

Curitiba, Paraná, 80030-110, Brazil
Novartis Investigative Site

Recife, Pernambuco, 50740-900, Brazil
Novartis Investigative Site

Niterói, Rio de Janeiro, 24020 096, Brazil
Novartis Investigative Site

Rio de Janeiro, Rio de Janeiro, 22211-230, Brazil
Novartis Investigative Site

Barretos, São Paulo, 14784 400, Brazil
Novartis Investigative Site

São Paulo, São Paulo, 01244-030, Brazil
Novartis Investigative Site

São Paulo, São Paulo, 04038-002, Brazil
Novartis Investigative Site

Salvador, 40323-010, Brazil
Novartis Investigative Site

Plovdiv, 4002, Bulgaria
Novartis Investigative Site

Rousse, 7002, Bulgaria
Novartis Investigative Site

Sofia, 1680, Bulgaria
Novartis Investigative Site

Calgary, Alberta, T2N 4Z6, Canada
Novartis Investigative Site

Vancouver, British Columbia, V5Z 1L7, Canada
Novartis Investigative Site

Hamilton, Ontario, L8N 3Z5, Canada
Novartis Investigative Site

Toronto, Ontario, M5T 2S8, Canada
Novartis Investigative Site

Rimouski, Quebec, G5L 5T1, Canada
Novartis Investigative Site

Guangzhou, Guangdong, 510000, China
Novartis Investigative Site

Guangzhou, Guangdong, 510080, China
Novartis Investigative Site

Shantou, Guangdong, 515000, China
Novartis Investigative Site

Haikou, Hainan, 570311, China
Novartis Investigative Site

Zhuzhou, Hunan, 412000, China
Novartis Investigative Site

Nanjing, Jiangsu, 210008, China
Novartis Investigative Site

Suzhou, Jiangsu, 215004, China
Novartis Investigative Site

Nanchang, Jiangxi, 330006, China
Novartis Investigative Site

Pingxiang, Jiangxi, 337000, China
Novartis Investigative Site

Changchun, Jilin, 130021, China
Novartis Investigative Site

Linyi, Shandong, 276000, China
Novartis Investigative Site

Chengdu, Sichuan, 610041, China
Novartis Investigative Site

Ürümqi, Xinjiang, 830001, China
Novartis Investigative Site

Ningbo, Zhejiang, 315016, China
Novartis Investigative Site

Wenzhou, Zhejiang, 325000, China
Novartis Investigative Site

Beijing, 100069, China
Novartis Investigative Site

Beijing, 100730, China
Novartis Investigative Site

Shanghai, 200127, China
Novartis Investigative Site

Xinxiang, 453099, China
Novartis Investigative Site

Barranquilla, Atlántico, 080020, Colombia
Novartis Investigative Site

Bucaramanga, Santander Department, 680003, Colombia
Novartis Investigative Site

Cali, Valle del Cauca Department, 760046, Colombia
Novartis Investigative Site

Brno, 638 00, Czechia
Novartis Investigative Site

Prague, 128 00, Czechia
Novartis Investigative Site

Uherské Hradiště, 686 01, Czechia
Novartis Investigative Site

Guatemala City, 01010, Guatemala
Novartis Investigative Site

Guatemala City, 01011, Guatemala
Novartis Investigative Site

Székesfehérvár, Fejér, 8000, Hungary
Novartis Investigative Site

Budapest, 1036, Hungary
Novartis Investigative Site

Budapest, H-1083, Hungary
Novartis Investigative Site

Gyula, 5700, Hungary
Novartis Investigative Site

Zalaegerszeg, 8900, Hungary
Novartis Investigative Site

Haifa, 3109601, Israel
Novartis Investigative Site

Ramat Gan, 5265601, Israel
Novartis Investigative Site

Nagoya, Aichi-ken, 4578510, Japan
Novartis Investigative Site

Nagoya, Aichi-ken, 4578511, Japan
Novartis Investigative Site

Sapporo, Hokkaido, 0608648, Japan
Novartis Investigative Site

Yokohama, Kanagawa, 222-0036, Japan
Novartis Investigative Site

Yokohama, Kanagawa-ku, 236-0004, Japan
Novartis Investigative Site

Sendai, Miyagi, 9838512, Japan
Novartis Investigative Site

Bunkyo Ku, Tokyo, 1138431, Japan
Novartis Investigative Site

Bunkyo Ku, Tokyo, 1138655, Japan
Novartis Investigative Site

Bunkyo-ku, Tokyo, 1138519, Japan
Novartis Investigative Site

Chuo Ku, Tokyo, 1048560, Japan
Novartis Investigative Site

Fuchū, Tokyo, 1838524, Japan
Novartis Investigative Site

Itabashi-ku, Tokyo, 1738610, Japan
Novartis Investigative Site

Meguro City, Tokyo, 153-8515, Japan
Novartis Investigative Site

Shinjuku-ku, Tokyo, 1608582, Japan
Novartis Investigative Site

Fukuoka, 8128582, Japan
Novartis Investigative Site

Miyazaki, 889-1692, Japan
Novartis Investigative Site

Osaka, 5458586, Japan
Novartis Investigative Site

Wroclaw, Lower Silesian Voivodeship, 52-210, Poland
Novartis Investigative Site

Bydgoszcz, 85-065, Poland
Novartis Investigative Site

Bydgoszcz, 85-168, Poland
Novartis Investigative Site

Bytom, 41 902, Poland
Novartis Investigative Site

Lodz, 90-338, Poland
Novartis Investigative Site

Warsaw, 00-874, Poland
Novartis Investigative Site

Warsaw, 04-141, Poland
Novartis Investigative Site

Braga, 4710243, Portugal
Novartis Investigative Site

Lisbon, 1050-034, Portugal
Novartis Investigative Site

Lisbon, 1349-019, Portugal
Novartis Investigative Site

Lisbon, 1649-035, Portugal
Novartis Investigative Site

Vila Nova de Gaia, 4434 502, Portugal
Novartis Investigative Site

Bratislava, 811 08, Slovakia
Novartis Investigative Site

Košice, 040 01, Slovakia
Novartis Investigative Site

Košice, 040 11, Slovakia
Novartis Investigative Site

Pretoria, Gauteng, 0002, South Africa
Novartis Investigative Site

Cape Town, Western Cape, 7405, South Africa
Novartis Investigative Site

Cape Town, Western Cape, 7500, South Africa
Novartis Investigative Site

Stellenbosch, Western Cape, 7600, South Africa
Novartis Investigative Site

Umhlanga, 4320, South Africa
Novartis Investigative Site

Santiago Compostela, A Coruna, 15706, Spain
Novartis Investigative Site

Elche, Alicante, 03203, Spain
Novartis Investigative Site

Badalona, Barcelona, 08916, Spain
Novartis Investigative Site

Santander, Cantabria, 39008, Spain
Novartis Investigative Site

Barcelona, Catalonia, 08003, Spain
Novartis Investigative Site

San Sebastian Reyes, Madrid, 28702, Spain
Novartis Investigative Site

Pamplona, Navarre, 31008, Spain
Novartis Investigative Site

Vigo, Pontevedra, 36214, Spain
Novartis Investigative Site

Barcelona, 08035, Spain
Novartis Investigative Site

Madrid, 28034, Spain
Novartis Investigative Site

Valencia, 46014, Spain
Novartis Investigative Site

Valladolid, 47012, Spain
Novartis Investigative Site

Songkhla, Hat Yai, 90110, Thailand
Novartis Investigative Site

Muang, Thailand, 12120, Thailand
Novartis Investigative Site

Bangkok, 10400, Thailand
Novartis Investigative Site

Bangkok, 10700, Thailand
Novartis Investigative Site

Ankara, Bilkent Cankaya, 06800, Turkey (Türkiye)
Novartis Investigative Site

Ankara, Etlik, 06010, Turkey (Türkiye)
Novartis Investigative Site

Istanbul, Umraniye, 34766, Turkey (Türkiye)
Novel Research LLC

Bellaire, Texas, 77401, United States
Paramount Med Rsrch and Consult LLC

Middleburg Heights, Ohio, 44130, United States
Parris and Associates Rheumatology

Lawrenceville, Georgia, 30044, United States
Pinnacle Research Group Llc

Anniston, Alabama, 36207, United States
Providence Medical Center

Burbank, California, 91505, United States
Robert A Hozman MD SC

Skokie, Illinois, 60076, United States
Sahni Rheumatology and Therapy

West Long Branch, New Jersey, 07764, United States
Shelby Research LLC

Memphis, Tennessee, 38119, United States
University Of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States
University of California San Diego

La Jolla, California, 92093, United States
University of Colorado

Aurora, Colorado, 80045, United States
Yale University School Of Medicine

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

SYSTEMIC LUPUS ERYTHEMATOSUS