New shot aims to protect kidneys in lupus patients

NCT ID NCT02770170

Completed Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding a new injectable drug called BI 655064 to standard treatment could better control kidney damage in people with active lupus nephritis. 121 adults with this serious kidney complication received either one of three drug doses or a placebo injection for one year, along with their usual care. The main goal was to see which dose best helped patients achieve a complete kidney response, meaning very low protein in urine and stable kidney function.

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Contacts and locations

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Locations

Academic Medical Research Institute

Los Angeles, California, 90022, United States
Addenbrooke's Hospital

Cambridge, CB2 0QQ, United Kingdom
Ajou University Hospital

Suwon, 16499, South Korea
Angeles University Foundation Medical Center

Angeles City, 2009, Philippines
Asklepios Klinik Altona

Hamburg, 22763, Germany
Azienda Ospedaliera Universitaria di Padova

Padua, 35128, Italy
CHU de Quebec-Universite Laval Research Centre

Québec, G1V 4G2, Canada
CHUC - Centro Hospitalar e Universitário de Coimbra, EPE

Coimbra, 3000-075, Portugal
CHULN, EPE - Hospital de Santa Maria

Lisbon, 1649-035, Portugal
Cebu Doctors Hospital

Cebu City, Cebu, 6000, Philippines
Cent.Clin.Hosp.Med.Univ.Lodz,Electrocard

Lodz, 92-213, Poland
Centro Hospitalar Universitário São João,EPE

Porto, 4200-319, Portugal
Chiangmai University

Chiang Mai, 50200, Thailand
Chong Hua Hospital

Cebu City, 6000, Philippines
Clinic Medical Center; Nowa Sol

Nowa Sól, 67-100, Poland
Clinical Centre Nis

Niš, 18000, Serbia
Columbia University Medical Center-New York Presbyterian Hospital

New York, New York, 10032, United States
Emory University

Atlanta, Georgia, 30322, United States
Feinstein Institute for Medical Research

Manhasset, New York, 11030, United States
Fundación Jiménez Díaz

Madrid, 28040, Spain
General Hospital of Athens "Laiko"

Athens, 115 27, Greece
General University Hospital Prague 2, Nephrology Clinic

Prague, 12808, Czechia
Guy's Hospital

London, SE1 9RT, United Kingdom
H. Central Dr Ignacio M. P.

San Luis Potosí City, 78240, Mexico
HOP Henri Mondor

Créteil, 94010, France
HOP La Pitié Salpêtrière

Paris, 75013, France
Hokkaido University Hospital

Hokkaido, Sapporo, 060-8648, Japan
Hope Clinical Research

Kissimmee, Florida, 34741, United States
Hospital Cardiologica Aguascalientes

Aguascalientes, 20230, Mexico
Hospital Curry Cabral, EPE

Lisbon, 1069-166, Portugal
Hospital Dr. Peset

Valencia, 46017, Spain
Hospital Hradec Kralove

Hradec Králové, 50005, Czechia
Hospital Raja Permaisuri Bainun

Ipoh, 30990, Malaysia
Hospital Tengku Ampuan Rahimah

Klang, 41200, Malaysia
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital Vall d'Hebron

Barcelona, 08035, Spain
Hospital of the University of Occupational and Environmental Health

Fukuoka, Kitakyushu, 807-8556, Japan
Institute of Rheumathology Prague

Prague, 12850, Czechia
Institute of Rheumatology, Belgrade

Belgrade, 11000, Serbia
Instituto Nacional de Cardiologia Ignacio Chavez

Mexico City, 14080, Mexico
Instituto Nacional de Cs Médicas y Nutrición S Zubiran

Mexico City, 14080, Mexico
Integral Rheumatology and Immunology Specialist

Plantation, Florida, 33324, United States
Integrity Clinical Research, LLC

Doral, Florida, 33166, United States
John Paul II Regional Hospital, Zamosc

Zamość, 22-400, Poland
Juntendo University Hospital

Tokyo, Bunkyo-ku, 113-8431, Japan
Keio University Hospital

Tokyo, Shinjuku-ku, 160-8582, Japan
King Chulalongkorn Memorial Hospital

Bangkok, 10330, Thailand
Leicester General Hospital

Leicester, LE5 4PW, United Kingdom
Mary Mediatrix Medical Center

Lipa City, Batangas, 4217, Philippines
Military Medical Academy

Belgrade, 11000, Serbia
NZOZ Centrum Medyczne AESKULAP,Private Prac, Radom

Radom, 26610, Poland
Naresuan University Hospital

Muang, 65000, Thailand
Norbert Barlicki University Clinical Hospital No.1, Lodz

Lodz, 90-153, Poland
Northwell Health

Great Neck, New York, 11021, United States
Office of Dr. Ramesh C. Gupta

Memphis, Tennessee, 38119, United States
Okayama University Hospital

Okayama, Okayama, 700-8558, Japan
Pramongkutklao Hospital

Bangkok, 10400, Thailand
Prince of Wales Hospital

Hong Kong, 999077, Hong Kong
Princess Alexandra Hospital

Woolloongabba, 4102, Australia
Queen Mary Hospital

Hong Kong, 999077, Hong Kong
Robert-Bosch-Krankenhaus GmbH

Stuttgart, 70376, Germany
Siriraj Hospital

Bangkok, 10700, Thailand
Southern Philippines Medical Center

Davao City, 8000, Philippines
St. Marianna University School of Medicine Hospital

Kanagawa, Kawasaki, 216-8511, Japan
The Prince of Wales Hospital

Randwick, New South Wales, 2031, Australia
Tohoku University Hospital

Miyagi, Sendai, 980-8574, Japan
Toronto Western Hospital

Toronto, Ontario, M5T 2S8, Canada
University Clinical Hospital in Bialystok I

Bialystok, 15-540, Poland
University General Hospital Attikon

Athens, 124 62, Greece
University General Hospital of Heraklion

Heraklion, Crete, 711 10, Greece
Universitätsklinikum Köln (AöR)

Cologne, 50937, Germany
Universitätsklinikum Schleswig-Holstein, Campus Lübeck

Lübeck, 23538, Germany
Universitätsmedizin Göttingen, Georg-August-Universität

Göttingen, 37075, Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz

Mainz, 55131, Germany

Conditions

Explore the condition pages connected to this study.

LUPUS NEPHRITIS