New inhaled drug shows promise in preventing deadly fungus in lung transplant patients

NCT ID NCT05037851

First seen May 14, 2026 ยท Last updated May 14, 2026

Summary

This study tested a new inhaled medication called opelconazole (PC945) to prevent a serious fungal lung infection (aspergillosis) in people who had a lung transplant. The trial included 102 participants and compared the safety and tolerability of the new drug against standard care over 12 weeks. The goal was to see if this treatment could be a safer or more effective way to protect transplant recipients from this dangerous infection.

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Contacts and locations

Locations

  • Clinical Research Site

    Phoenix, Arizona, 85013, United States

  • Clinical Research Site

    La Jolla, California, 92037, United States

  • Clinical Research Site

    Los Angeles, California, 90095, United States

  • Clinical Research Site

    Jacksonville, Florida, 32224, United States

  • Clinical Research Site

    Tampa, Florida, 33606, United States

  • Clinical Research Site

    Maywood, Illinois, 60153, United States

  • Clinical Research Site

    New York, New York, 10016, United States

  • Clinical Research Site

    The Bronx, New York, 10467, United States

  • Clinical Research Site

    Philadelphia, Pennsylvania, 19104, United States

  • Clinical Research Site

    Philadelphia, Pennsylvania, 19140, United States

  • Clinical Research Site

    Pittsburgh, Pennsylvania, 15213, United States

  • Clinical Research Site

    Nashville, Tennessee, 37232, United States

  • Clinical Research Site

    Dallas, Texas, 75246, United States

  • Clinical Research Site

    Edmonton, T6G 1Z1, Canada

  • Clinical Research Site

    Toronto, M5G 2N2, Canada

  • Clinical Research Site 1

    Houston, Texas, 77030, United States

  • Clinical Research Site 2

    Houston, Texas, 77030, United States

  • Clinical Research Site 3

    Houston, Texas, 77030, United States

  • Research Site

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.