New triple therapy aims to shrink lung tumors better than current standard

NCT ID NCT07005336

First seen Jan 31, 2026 · Last updated May 14, 2026 · Updated 10 times

Summary

This study tests whether adding the experimental drug uliledlimab to a standard immunotherapy (sintilimab) and chemotherapy can help people with advanced non-small cell lung cancer live longer without their cancer growing. About 150 adults who have not had prior treatment for their advanced lung cancer will be randomly assigned to receive either the triple combination or the standard double combination. The main goal is to see if the new combination delays cancer progression.

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Contacts and locations

Locations

  • Anhui Provincial Cancer Hospital

    Hefei, China

  • Beijing Chest Hospital

    Beijing, China

  • Binzhou Medical University Hospital

    Binzhou, China

  • Chongqing University Three Gorges Hospital

    Chongqing, China

  • First Hospital of Shanxi Medical University

    Taiyuan, China

  • General Hospital of Ningxia Medical University

    Yinchuan, China

  • Guangxi Medical University Cancer Hospital

    Nanning, China

  • Harbin Medical University Cancer Hospital

    Ha’erbin, China

  • Hubei Cancer Hospital

    Wuhan, China

  • Jiangmen Central Hospital

    Jiangmen, China

  • Linyi People's Hospital

    Linyi, China

  • Lishui Central Hospital

    Lishui, China

  • Shanghai Chest Hospital

    Shanghai, China

  • Shanxi Provincial Cancer Hospital

    Taiyuan, China

  • Sichuan Cancer Hospital

    Chengdu, China

  • The First Affiliated Hospital of Anhui Medical University

    Hefei, China

  • The First Affiliated Hospital of Guangxi Medical University

    Nanning, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, China

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, China

  • The First Affiliated Hospital of Xinxiang Medical University

    Xinxiang, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, China

  • The Second Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, China

  • The Second People's Hospital of Neijiang

    Neijiang, China

  • The Second People's Hospital of Yibin

    Yibin, China

  • Xiangyang Central Hospital

    Xiangyang, China

  • Yunan Cancer Hospital

    Kunming, China

  • Zhoukou Central Hospital

    Zhoukou, China

Conditions

Explore the condition pages connected to this study.