Promising lung cancer drug trial halted midway
NCT ID NCT04154956
First seen May 20, 2026 · Last updated May 24, 2026 · Updated 1 time
Summary
This study tested a new drug, tusamitamab ravtansine, against standard chemotherapy (docetaxel) in 389 adults with advanced non-small-cell lung cancer that had stopped responding to previous treatments. The drug targets a specific marker (CEACAM5) on cancer cells. The trial was terminated early, so final results are not yet available.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ca & Hem Center Of W Michigan- Site Number : 8400016
Grand Rapids, Michigan, 49546, United States
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Centro Avancado de Oncologia CECAN - Liga Contra o Cancer- Site Number : 0760026
Natal, Rio Grande do Norte, 59062-000, Brazil
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Centro Regional Integrado De Oncologia - CRIO- Site Number : 0760002
Fortaleza, Ceará, 60336-232, Brazil
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Clínica de Oncologia Reichow Site Number : 0760023
Blumenau, Santa Catarina, 89010-340, Brazil
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Florida Cancer Specialists North Division- Site Number : 8400019
St. Petersburg, Florida, 33705, United States
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Florida Cancer Specialists South Division- Site Number : 8400020
Fort Myers, Florida, 33901, United States
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Hospital Sirio Libanes- Site Number : 0760018
São Paulo, São Paulo, 01308050, Brazil
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Hospital de Base Sao Jose do Rio Preto Site Number : 0760001
São José do Rio Preto, São Paulo, 15090-000, Brazil
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Investigational Site Number : 0320001
Buenos Aires, 1426ANZ, Argentina
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Investigational Site Number : 0320002
Salta, 4400, Argentina
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Investigational Site Number : 0320003
Viedma, Río Negro Province, R8500ACE, Argentina
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Investigational Site Number : 0320004
Buenos Aires, C1125ABD, Argentina
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Investigational Site Number : 0320009
CABA, Buenos Aires, C1019ABS, Argentina
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Investigational Site Number : 0320012
Capital Federal, Buenos Aires, 1012, Argentina
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Investigational Site Number : 0320014
Córdoba, ZCX5000AAI, Argentina
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Investigational Site Number : 0360001
Woolloongabba, Queensland, 4102, Australia
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Investigational Site Number : 0360002
Blacktown, New South Wales, 2148, Australia
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Investigational Site Number : 0360003
Waratah, New South Wales, 2298, Australia
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Investigational Site Number : 0560001
Leuven, 3000, Belgium
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Investigational Site Number : 0560002
Woluwe-Saint-Lambert, 1200, Belgium
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Investigational Site Number : 0560003
Liège, 4000, Belgium
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Investigational Site Number : 0560004
Edegem, B-2650, Belgium
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Investigational Site Number : 0560005
Ghent, 9000, Belgium
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Investigational Site Number : 0560006
Anderlecht, 1070, Belgium
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Investigational Site Number : 1000001
Sofia, 1797, Bulgaria
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Investigational Site Number : 1000003
Sofia, 1618, Bulgaria
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Investigational Site Number : 1000004
Sofia, 1330, Bulgaria
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Investigational Site Number : 1000007
Plovdiv, 4002, Bulgaria
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Investigational Site Number : 1000008
Burgas, 8000, Bulgaria
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Investigational Site Number : 1000010
Pleven, 5800, Bulgaria
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Investigational Site Number : 1240003
Greenfield Park, Quebec, J4V 2H1, Canada
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Investigational Site Number : 1240010
Montreal, Quebec, H1T 1P7, Canada
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Investigational Site Number : 1520001
Viña del Mar, Valparaiso, 2520598, Chile
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Investigational Site Number : 1520002
Santiago, Reg Metropolitana de Santiago, 8420383, Chile
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Investigational Site Number : 1520006
Santiago, Reg Metropolitana de Santiago, 7500921, Chile
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Investigational Site Number : 1520007
Santiago, Reg Metropolitana de Santiago, 7500713, Chile
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Investigational Site Number : 1520009
Santiago, Reg Metropolitana de Santiago, 7650568, Chile
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Investigational Site Number : 1560001
Guangzhou, 510080, China
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Investigational Site Number : 1560005
Harbin, 150081, China
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Investigational Site Number : 1560006
Wuhan, 430079, China
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Investigational Site Number : 1560009
Changchun, 130012, China
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Investigational Site Number : 1560010
Changchun, 130021, China
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Investigational Site Number : 1560011
Hangzhou, 310022, China
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Investigational Site Number : 1560012
Nanning, 530021, China
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Investigational Site Number : 1560015
Changsha, 410006, China
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Investigational Site Number : 1560016
Zhanjiang, 524001, China
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Investigational Site Number : 1560017
Guangzhou, 510515, China
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Investigational Site Number : 1560019
Nanjing, 210009, China
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Investigational Site Number : 1560021
Hangzhou, 310014, China
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Investigational Site Number : 1560023
Nanjing, 210006, China
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Investigational Site Number : 1560024
Fuzhou, 350008, China
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Investigational Site Number : 1560025
Hangzhou, 310003, China
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Investigational Site Number : 1560026
Beijing, 100142, China
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Investigational Site Number : 1560032
Chengdu, 610041, China
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Investigational Site Number : 1560033
Hangzhou, 310009, China
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Investigational Site Number : 1560036
Guangzhou, 510095, China
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Investigational Site Number : 1560037
Guangzhou, 510163, China
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Investigational Site Number : 1560038
Chengdu, 610041, China
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Investigational Site Number : 1560039
Changsha, 410011, China
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Investigational Site Number : 1560040
Zhengzhou, 450008, China
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Investigational Site Number : 1560041
Zhengzhou, 450003, China
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Investigational Site Number : 1560043
Chongqing, 400042, China
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Investigational Site Number : 1560044
Chongqing, 400038, China
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Investigational Site Number : 1560045
Tianjin, 300060, China
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Investigational Site Number : 1560047
Jinan, 250013, China
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Investigational Site Number : 1560050
Huizhou, 516001, China
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Investigational Site Number : 2500001
Marseille, 13015, France
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Investigational Site Number : 2500002
Saint-Mandé, 94160, France
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Investigational Site Number : 2500003
Rennes, 35033, France
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Investigational Site Number : 2500004
Villejuif, 94800, France
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Investigational Site Number : 2500006
Créteil, 94010, France
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Investigational Site Number : 2500007
Grenoble, 38043, France
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Investigational Site Number : 2500008
Caen, 14076, France
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Investigational Site Number : 2500009
Pierre-Bénite, 69495, France
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Investigational Site Number : 2500010
Bordeaux, 33076, France
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Investigational Site Number : 2500011
Paris, 75231, France
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Investigational Site Number : 2500012
Saint-Herblain, 44800, France
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Investigational Site Number : 2500013
Montpellier, 34295, France
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Investigational Site Number : 2500014
Paris, 75970, France
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Investigational Site Number : 2760001
Heidelberg, 69126, Germany
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Investigational Site Number : 2760002
Essen, 45147, Germany
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Investigational Site Number : 3000001
Athens, 11527, Greece
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Investigational Site Number : 3000003
Heraklion, 71500, Greece
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Investigational Site Number : 3000004
Ioannina, 455 00, Greece
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Investigational Site Number : 3000005
Athens, 11526, Greece
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Investigational Site Number : 3000006
Thessaloniki, 54645, Greece
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Investigational Site Number : 3480003
Budapest, 1121, Hungary
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Investigational Site Number : 3480005
Kaposvár, 7400, Hungary
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Investigational Site Number : 3480007
Budapest, 1125, Hungary
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Investigational Site Number : 3760001
Haifa, 3109601, Israel
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Investigational Site Number : 3760002
Kfar Saba, 44281, Israel
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Investigational Site Number : 3760003
Petah Tikva, 49100, Israel
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Investigational Site Number : 3800001
Milan, 20133, Italy
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Investigational Site Number : 3800003
Orbassano, Torino, 10043, Italy
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Investigational Site Number : 3800004
Ravenna, Emilia-Romagna, 48121, Italy
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Investigational Site Number : 3800005
Rozzano, Milano, 20089, Italy
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Investigational Site Number : 3800006
Catania, Italy
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Investigational Site Number : 3920001
Hirakata-shi, Osaka, 573-1191, Japan
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Investigational Site Number : 3920002
Nagoya, Aichi-ken, 460-0001, Japan
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Investigational Site Number : 3920003
Osaka, Osaka, 541-8567, Japan
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Investigational Site Number : 3920004
Sunto-gun, Shizuoka, 411-8777, Japan
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Investigational Site Number : 3920005
Yokohama, Kanagawa, 241-8515, Japan
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Investigational Site Number : 3920006
Kanazawa, Ishikawa-ken, 920-8641, Japan
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Investigational Site Number : 3920007
Wakayama, Wakayama, 641-8510, Japan
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Investigational Site Number : 3920008
Kurume-shi, Fukuoka, 830-0011, Japan
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Investigational Site Number : 3920009
Natori-shi, Miyagi, 981-1293, Japan
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Investigational Site Number : 3920010
Ube-shi, Yamaguchi, 755-0241, Japan
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Investigational Site Number : 3920011
Bunkyo-ku, Tokyo, 113-8603, Japan
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Investigational Site Number : 3920012
Fukuoka, Fukuoka, 810-8563, Japan
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Investigational Site Number : 3920013
Osaka Sayama-shi, Osaka, 589-8511, Japan
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Investigational Site Number : 3920015
Nagoya, Aichi-ken, 464-8681, Japan
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Investigational Site Number : 3920016
Sapporo, Hokkaido, 003-0804, Japan
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Investigational Site Number : 3920017
Himeji-shi, Hyōgo, 670-8520, Japan
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Investigational Site Number : 3920018
Mitaka-shi, Tokyo, 181-8611, Japan
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Investigational Site Number : 4100001
Seoul, 06591, South Korea
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Investigational Site Number : 4100003
Seoul, Seoul-teukbyeolsi, 06351, South Korea
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Investigational Site Number : 4100004
Seoul, Seoul-teukbyeolsi, 07061, South Korea
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Investigational Site Number : 4100005
Cheongju-si, North Chungcheong, 28644, South Korea
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Investigational Site Number : 4100006
Seoul, Seoul-teukbyeolsi, 03722, South Korea
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Investigational Site Number : 4100007
Seoul, Seoul-teukbyeolsi, 05505, South Korea
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Investigational Site Number : 4100008
Busan, Busan, 48108, South Korea
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Investigational Site Number : 4840003
Cuauhtémoc, Mexico City, 06700, Mexico
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Investigational Site Number : 5280003
's-Hertogenbosch, 5223 GZ, Netherlands
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Investigational Site Number : 5280004
Breda, 4818 CK, Netherlands
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Investigational Site Number : 5280005
Utrecht, 3543 AZ, Netherlands
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Investigational Site Number : 6160001
Warsaw, 02-781, Poland
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Investigational Site Number : 6160004
Olsztyn, Warmian-Masurian Voivodeship, 10-357, Poland
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Investigational Site Number : 6200001
Lisbon, 1769, Portugal
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Investigational Site Number : 6200002
Almada, 2801-951, Portugal
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Investigational Site Number : 6200004
Lisbon, 1998-018, Portugal
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Investigational Site Number : 6200005
Porto, 4099-001, Portugal
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Investigational Site Number : 6200006
Porto, 4100-180, Portugal
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Investigational Site Number : 6420003
Bucaresti, 022328, Romania
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Investigational Site Number : 6420005
Timișoara, 300166, Romania
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Investigational Site Number : 6420008
Alba Iulia, 510077, Romania
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Investigational Site Number : 6420009
Brasov, 500152, Romania
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Investigational Site Number : 6420010
Cluj-Napoca, 400124, Romania
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Investigational Site Number : 6420011
Cluj-Napoca, 407280, Romania
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Investigational Site Number : 6420012
Otopeni, 75100, Romania
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Investigational Site Number : 6430001
Moscow, 115478, Russia
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Investigational Site Number : 6430003
Saint Petersburg, 197758, Russia
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Investigational Site Number : 7020001
Singapore, 308433, Singapore
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Investigational Site Number : 7020002
Singapore, 329563, Singapore
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Investigational Site Number : 7240001
L'Hospitalet de Llobregat, Barcelona [Barcelona], 08908, Spain
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Investigational Site Number : 7240002
Madrid, 28041, Spain
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Investigational Site Number : 7240004
Málaga, 29010, Spain
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Investigational Site Number : 7240005
Barcelona, Barcelona [Barcelona], 08036, Spain
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Investigational Site Number : 7240006
Pamplona, Navarre, 31008, Spain
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Investigational Site Number : 7240007
Barcelona, Barcelona [Barcelona], 08028, Spain
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Investigational Site Number : 7240008
Valencia, 46026, Spain
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Investigational Site Number : 7240009
Madrid / Madrid, Madrid, Comunidad de, 28040, Spain
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Investigational Site Number : 7240011
Seville, 41013, Spain
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Investigational Site Number : 7920001
Istanbul, 34303, Turkey (Türkiye)
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Investigational Site Number : 7920002
Adana, 01250, Turkey (Türkiye)
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Investigational Site Number : 7920005
Istanbul, 34214, Turkey (Türkiye)
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Investigational Site Number : 7920006
Istanbul, 34722, Turkey (Türkiye)
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Investigational Site Number : 7920007
Izmir, Turkey (Türkiye)
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Investigational Site Number : 7920008
Adana, 01060, Turkey (Türkiye)
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Investigational Site Number : 7920009
Malatya, Turkey (Türkiye)
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Investigational Site Number : 7920010
Izmir, Turkey (Türkiye)
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Investigational Site Number : 7920011
Ankara, 06800, Turkey (Türkiye)
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Investigational Site Number : 7920012
Adana, 01140, Turkey (Türkiye)
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Investigational Site Number : 7920014
Kocaeli, 41100, Turkey (Türkiye)
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Lankenau Hospital Cancer Center- Site Number : 8400017
Wynnewood, Pennsylvania, 19096-3411, United States
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Medical College of Wisconsin- Site Number : 8400006
Milwaukee, Wisconsin, 53226, United States
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Renovatio Clinical - Site Number : 8400013
The Woodlands, Texas, 77380, United States
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Renovatio Clinical- Site Number : 8400032
El Paso, Texas, 79915, United States
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Roswell Park Cancer Institute Site Number : 8400011
Buffalo, New York, 14263-0001, United States
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~Instituto De Oncologia Parana- Site Number : 0760008
Curitiba, Paraná, 80530-010, Brazil
Conditions
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