New Two-Drug combo tested in major lung cancer trial

NCT ID NCT04294810

Summary

This large, completed Phase 3 trial tested whether adding a new drug called tiragolumab to an existing immunotherapy (atezolizumab) works better than the immunotherapy alone for people with a specific type of advanced lung cancer who haven't had prior treatment. The study involved 620 participants and aimed to see if the combination could help patients live longer without their cancer getting worse, while monitoring safety. It focused on patients whose cancer cells had high levels of a marker called PD-L1 and did not have certain other genetic mutations.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AVIX Investigación Clínica S.C

    Monterrey, Nuevo León, 64710, Mexico

  • Adana Baskent University Hospital

    Adana, 01120, Turkey (Türkiye)

  • Aichi Cancer Center

    Aichi, 464-8681, Japan

  • Ajou University Medical Center

    Gyeonggi-do, 16499, South Korea

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Asst Di Monza

    Monza, Lombardy, 20900, Italy

  • Austin Hospital Olivia Newton John Cancer Centre

    Heidelberg, Victoria, 3084, Australia

  • Azienda Ospedaliera Di Perugia Ospedale s. Maria Della Misericordia

    Perugia, Umbria, 06156, Italy

  • Azienda Ospedaliera San Camillo Forlanini

    Rome, Lazio, 00151, Italy

  • Azienda Ospedaliera San Giuseppe Moscati

    Avellino, Campania, 83100, Italy

  • Azienda Sanitaria Ospedaliera S Luigi Gonzaga

    Orbassano, Piedmont, 10043, Italy

  • Beijing Cancer Hospital

    Beijing, 100142, China

  • CHUV

    Lausanne, 1011, Switzerland

  • Chang Gung Memorial Hospital - Linkou Branch

    Guishan Dist., 33305, Taiwan

  • Chongqing Cancer Hospital

    Chongqing, 400030, China

  • Chonnam National University Hwasun Hospital

    Jeollanam-do, 58128, South Korea

  • Chulalongkorn Hospital

    Bangkok, 10330, Thailand

  • Chungbuk National University Hospital

    Cheongju-si, 28644, South Korea

  • City Clinical Hospital #4

    Dnipropetrovsk, 49102, Ukraine

  • Clinica Internacional, Sede San Borja

    Lima, Lima 41, Peru

  • Clinica Ricardo Palma

    San Isidro, Lima 27, Peru

  • Clinical Center of Serbia

    Belgrade, 11000, Serbia

  • Cryptex Investigacion Clinica SA de CV

    México, Mexico CITY (federal District), 06100, Mexico

  • Cuidados oncologicos

    Querétaro City, Querétaro, 76000, Mexico

  • Faculty of Med. Siriraj Hosp.

    Bangkok, 10700, Thailand

  • First Affiliated Hospital of Medical College of Xi'an Jiaotong University

    Xi'an, 710061, China

  • Fudan University Shanghai Cancer Center

    Shanghai, 200120, China

  • Fujian Cancer Hospital

    Fuzhou, 350014, China

  • Gachon University Gil Medical Center

    Incheon, 21565, South Korea

  • Gemeinschaftspraxis für Hämatologie und Onkologie

    Münster, 48153, Germany

  • Goztepe Prof.Dr. Suleyman Yalcin City Hospital

    Kadiköy, 34722, Turkey (Türkiye)

  • HOCH Health Ostschweiz, Kantonsspital St. Gallen

    Sankt Gallen, 9000, Switzerland

  • Hacettepe University Medical Faculty

    Ankara, 06100, Turkey (Türkiye)

  • Hagaziekenhuis, locatie Leyweg

    The Hague, 2545 AA, Netherlands

  • Hainan General Hospital

    Haikou, 570311, China

  • Harbin Medical University Cancer Hospital

    Harbin, 150081, China

  • Health Pharma Professional Research

    CD Mexico, Mexico CITY (federal District), 03810, Mexico

  • Hosp Clinico Univ Lozano Blesa

    Zaragoza, 50009, Spain

  • Hospital 12 de Octubre

    Madrid, 28041, Spain

  • Hospital General Universitario de Alicante

    Alicante, 03010, Spain

  • Hospital Regional Universitario de Malaga

    Málaga, 29010, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Germans Trias i Pujol

    Badalona, Barcelona, 08916, Spain

  • Hospital Universitario Puerta de Hierro - Majadahonda

    Madrid, 28222, Spain

  • Hospital Universitario Virgen del Rocío

    Madrid, 41013, Spain

  • Hospital de Cancer de Barretos

    Barretos, São Paulo, 14784-400, Brazil

  • IOV - Istituto Oncologico Veneto - IRCCS

    Padua, Veneto, 35128, Italy

  • Inonu University Medical Faculty of Medicine

    Malatya, 44280, Turkey (Türkiye)

  • Inselspital Bern

    Bern, 3010, Switzerland

  • Institute of Oncology

    Saint Petersburg, Sankt-Peterburg, 189646, Russia

  • Instituto Nacional de Enfermedades Neoplasicas

    Lima, 15038, Peru

  • Instituto Regional de Enfermedades Neoplásicas del Sur

    Arequipa, 5154, Peru

  • Irccs Istituto Europeo di Oncologia (IEO)

    Milan, Lombardy, 20141, Italy

  • Istanbul University Cerrahpasa Faculty of Medicine

    Istanbul, 34098, Turkey (Türkiye)

  • Istituto Clinico Humanitas

    Rozzano, Lombardy, 20089, Italy

  • Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale

    Naples, Campania, 80131, Italy

  • Izmir Dr. Suat Seren Gogus Hastaliklari ve Cerrahisi Egitim ve Arastirma Hastanesi

    Izmir, 35110, Turkey (Türkiye)

  • Jinan Central Hospital

    Jinan, 250013, China

  • Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház

    Szolnok, 5004, Hungary

  • Kangbuk Samsung Medical Center

    Seoul, 03181, South Korea

  • Kaohsiung Chang Gung Memorial Hospital

    Kaohsiung City, 83301, Taiwan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    Kaohsiung City, 807, Taiwan

  • Kindai University Hospital

    Osaka, 589-8511, Japan

  • Klinik Penzing

    Vienna, 1140, Austria

  • Klinik Schillerhöhe

    Stuttgart, 70376, Germany

  • Korea University Guro Hospital

    Seoul, 08308, South Korea

  • Krankenhaus Martha-Maria Halle-Doelau gGmbH

    Halle, 06120, Germany

  • Krankenhaus Nord - Klinik Floridsdorf

    Vienna, 1210, Austria

  • Krankenhaus Nordwest

    Frankfurt, 60488, Germany

  • Kyushu University Hospital

    Fukuoka, 812-8582, Japan

  • LungenClinic Großhansdorf GmbH

    Großhansdorf, 22927, Germany

  • ME Kryviy Rih Oncology Dispensary of Dnipropetrovs?k Regional Council

    Kryvyi Rih, 50048, Ukraine

  • MEDSI Clinical Hospital on Pyatnitsky Highway

    Moscow, Moscow Oblast, 143422, Russia

  • Main Military Clinical Hospital named after N.N. Burdenko

    Moscow, Moscow Oblast, 105229, Russia

  • Matrai Gyogyintezet

    Mátraháza, 3233, Hungary

  • Medisch Centrum Leeuwarden

    Leeuwarden, 8934 AD, Netherlands

  • Meizhou People's Hospital

    Meizhou, 514031, China

  • Metropolitan Hospital

    Athens, 185 47, Greece

  • NHO Kinki-Chuo Chest Medical Center

    Sakaishi, 591-8555, Japan

  • Nantong Tumor Hospital

    Nantong, 226361, China

  • National Cancer Center Hospital

    Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    Chiba, 277-8577, Japan

  • National Cheng Kung Uni Hospital

    Tainan, 704, Taiwan

  • National Taiwan University Hospital

    Zhongzheng Dist., 10048, Taiwan

  • Niigata Cancer Center Hospital

    Niigata, 951-8566, Japan

  • Northwest Cancer Specialists - Vancouver

    Vancouver, Washington, 98684, United States

  • Onc & Hem Assoc SW Virginia

    Salem, Virginia, 24153, United States

  • Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda

    Ijuí, Rio Grande do Sul, 98700-000, Brazil

  • Ordensklinikum Linz Elisabethinen

    Linz, 4020, Austria

  • Orszagos Koranyi TBC es Pulmonologiai Intezet

    Budapest, 1121, Hungary

  • Osaka International Cancer Institute

    Osaka, 541-8567, Japan

  • Peter Maccallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Policlinico Universitario "Agostino Gemelli"

    Rome, Lazio, 00168, Italy

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

  • Ramathibodi Hospital

    Bangkok, 10400, Thailand

  • Rocky Mountain Cancer Center - Denver

    Denver, Colorado, 80220, United States

  • SCRI Florida Cancer Specialists North

    St. Petersburg, Florida, 33705, United States

  • SCRI Florida Cancer Specialists PAN

    Tallahassee, Florida, 32308, United States

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • SLK Kliniken Heilbronn GmbH, Standort Fachklinik Löwenstein

    Löwenstein, 74245, Germany

  • Saitama Cancer Center

    Saitama, 362-0806, Japan

  • Samsung Medical Center

    Seoul, 6351, South Korea

  • Sendai Kousei Hospital

    Miyagi, 980-0873, Japan

  • Seoul National University Bundang Hospital

    Gyeonggi-do, 13620, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, 03722, South Korea

  • Shanghai Pulmonary Hospital

    Shanghai, 200433, China

  • Shizuoka Cancer Center

    Shizuoka, 411-8777, Japan

  • Sir Run Run Shaw Hospital Zhejiang University

    Hangzhou, 310016, China

  • Songklanagarind Hospital

    Songkhla, 90110, Thailand

  • Sotiria Hospital

    Athens, 104 31, Greece

  • St. Petersburg Clinical Scientific Center of special services medical assis (oncology)

    Saint Petersburg, Sankt-Peterburg, 197758, Russia

  • St. Petersburg Med Univ

    Saint Petersburg, Sankt-Peterburg, 197089, Russia

  • St. Vincent's Hospital

    Suwon, 442-723, South Korea

  • Taichung Veterans General Hospital

    Taichung, 407, Taiwan

  • Taipei Medical University ?Shuang Ho Hospital

    New Taipei City, 23561, Taiwan

  • Taipei Veterans General Hospital

    Taipei, 112, Taiwan

  • The 1st Affiliated Hospital of Nanchang Unversity

    Nanchang, 330200, China

  • The Cancer Institute Hospital of JFCR

    Tokyo, 135-8550, Japan

  • The First Affiliated Hospital of Xiamen University

    Xiamen, 361003, China

  • The First Hospital of Jilin University

    Changchun, 130021, China

  • US oncology research at Minnesota Oncology

    Saint Paul, Minnesota, 55102, United States

  • University Hospital Medical Center Bezanijska kosa

    Belgrade, 11080, Serbia

  • University Hospital of Larissa

    Larissa, 411 10, Greece

  • Uniwersyteckie Centrum Kliniczne

    Gda?sk, 80-214, Poland

  • Uzhgorod Nat. University Central Municip Hosp

    Uzhhorod, 88000, Ukraine

  • Virginia Cancer Specialists (Fairfax) - USOR

    Fairfax, Virginia, 22031, United States

  • Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie

    Olsztyn, 10-357, Poland

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

  • Wielkopolskie Centrum Pulmonologii i Torakochirurgii w Poznaniu

    Poznan, 60-569, Poland

  • Yale Cancer Center

    New Haven, Connecticut, 06520, United States

  • Zhejiang Cancer Hospital

    Zhejiang, 310022, China

  • Zhongshan Hospital Fudan University

    Shanghai, 200032, China

  • Ziekenhuis Gelderse Vallei

    Ede, 6716 RP, Netherlands

Conditions

Explore the condition pages connected to this study.