New hope for lung cancer patients when first treatments fail

NCT ID NCT04884282

Summary

This study is testing whether adding an experimental cancer vaccine called Tedopi to standard second-line drugs (docetaxel or nivolumab) can help control metastatic lung cancer that has progressed after initial treatment. It will involve about 105 patients who have a specific genetic marker (HLA-A2+) and whose cancer initially responded to but then stopped responding to first-line chemo-immunotherapy. The main goal is to see if more patients are alive one year after starting these combination treatments.

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Contacts and locations

Locations

  • AO Busto Arstizio PO Saronno

    Saronno, Varese, Italy

  • AOOR Papardo-Piemonte

    Messina, Italy

  • AOU "Maggiore della Carità"

    Novara, Italy

  • ASST Sette Laghi

    Varese, Italy

  • Azienda Ospedaliera di Perugia

    Perugia, Italy

  • Azienda Ospedaliero-Universitaria Careggi

    Florence, Italy

  • Centre Hospitalier de Cholet

    Cholet, 49300, France

  • Clinica Mi Tres Torres - UOMI Cancer Center

    Barcelona, 08017, Spain

  • Complejo Hospitalario Universitario A Coruña (CHUAC)

    A Coruña, 15006, Spain

  • GHR Mulhouse Sud Alsace - Hôpital Emile Muller

    Mulhouse, 68100, France

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Regional de Málaga - Hospital Civil

    Málaga, 29011, Spain

  • Hospital de Mataró

    Mataró, 08304, Spain

  • IRCCS - Arcispedale Santa Maria Nuova

    Reggio Emilia, Italy

  • Institut Sainte Catherine

    Avignon, 84918, France

  • Istituto Nazionale Tumori "Regina Elena"

    Roma, 00144, Italy

  • Istituto Oncologico Veneto

    Padua, 35128, Italy

  • Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

    Meldola, Forlì, 47014, Italy

  • Nouvel Hôpital Civil - Hopitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

  • Ospedale Mater Salutis Legnago

    Legnago, Verona, 37045, Italy

  • Ospedale Sacro Cuore Don Calabria

    Negrar, Verona, Italy

  • Ospedale San Paolo

    Civitavecchia, Italy

  • Vall d'Hebron Universitary Hospital

    Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.