New combo tested to fight advanced lung cancer after first treatment fails

NCT ID NCT03003468

Summary

This study tested whether adding a new drug called Imprime PGG to an existing immunotherapy (pembrolizumab) could help control advanced lung cancer that had worsened after initial chemotherapy. It involved 35 adults with metastatic non-small cell lung cancer. The research first aimed to find a safe dose of the combination, then to see if it could delay cancer growth longer than expected with pembrolizumab alone.

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Contacts and locations

Locations

  • Indiana Univeristy Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Penn State Cancer Institute

    Hershey, Pennsylvania, 17033, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60612, United States

  • University of Iowa Hospital and Clinics

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.