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Scientists test 'DNA Sabotage' drugs to supercharge lung cancer radiation

NCT ID NCT04550104

Recruiting now Disease control Sponsor: University of Leeds Source: ClinicalTrials.gov ↗

Summary

This study aims to make standard radiation therapy more effective for non-small cell lung cancer. Researchers are testing new drugs designed to block cancer cells' ability to repair the DNA damage caused by radiation, which could help kill more cancer cells. The trial will find the safest and most effective dose of these drugs when combined with radiation, followed by immunotherapy for some patients. It involves about 200 adults with specific stages of lung cancer who are scheduled to receive curative radiation.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Belfast City Hospital

    RECRUITING

    Belfast, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Birmingham Heartlands Hospital

    RECRUITING

    Birmingham, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Freeman Hospital, Newcastle upon Tyne Hospitals NHS Trust

    RECRUITING

    Newcastle upon Tyne, United Kingdom

    Contact

    Contact Email: •••••@•••••

  • St Bartholomew's Hospitals

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St James's University Hospital

    RECRUITING

    Leeds, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, United Kingdom

    Contact Email: •••••@•••••

    Contact

    Contact

  • The Clatterbridge Cancer Centre

    RECRUITING

    Liverpool, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Royal Marsden Hospital Chelsea

    RECRUITING

    Chelsea, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • The Royal Marsden Sutton

    RECRUITING

    Sutton, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • University College Hospital London

    RECRUITING

    London, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Velindre Cancer Centre

    RECRUITING

    Cardiff, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Western General Hospital

    RECRUITING

    Edinburgh, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Weston Park Hospital

    RECRUITING

    Sheffield, United Kingdom

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CANCER