New drug challenges standard treatment in major lung cancer trial

NCT ID NCT06767514

Recruiting now Disease control Sponsor: Summit Therapeutics Source: ClinicalTrials.gov ↗

Summary

This large Phase 3 trial is testing whether a new immunotherapy drug called ivonescimab works better than the current standard drug (pembrolizumab) for people with advanced non-small cell lung cancer that has spread and shows high levels of a specific marker called PD-L1. The study will enroll 780 adults who haven't had previous treatment for their advanced cancer, measuring how long patients live and how long the cancer stays controlled. Researchers are looking to see if ivonescimab helps patients live longer or delays cancer growth better than the existing treatment.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Changzhou, Jiangsu, China
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Wenzhou, Zhejiang, China
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Chandler, Arizona, 85224, United States
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Phoenix, Arizona, 85006, United States
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Hot Springs, Arkansas, 71913, United States
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Cerritos, California, 90703, United States
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Glendale, California, 91204, United States
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Irvine, California, 92612, United States
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Los Angeles, California, 90067, United States
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Mountain View, California, 94040, United States
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Murrieta, California, 92562, United States
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Newport Beach, California, 92663, United States
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Roseville, California, 95661, United States
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Sacramento, California, 95816, United States
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San Diego, California, 92123, United States
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San Francisco, California, 94115, United States
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Santa Ana, California, 92705, United States
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Whittier, California, 90602, United States
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Aurora, Colorado, 80045, United States
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Grand Junction, Colorado, 81505, United States
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Greeley, Colorado, 80631, United States
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Lone Tree, Colorado, 80124, United States
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Loveland, Colorado, 80538, United States
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Fort Lauderdale, Florida, 33317, United States
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Hialeah, Florida, 33013, United States
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Jacksonville, Florida, 32256, United States
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Miami, Florida, 33155, United States
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North Venice, Florida, 34275, United States
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Orlando, Florida, 32822, United States

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Pensacola, Florida, 32504, United States
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Plantation, Florida, 33322, United States
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Plantation, Florida, 33323, United States
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Tallahassee, Florida, 32308, United States
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Tamarac, Florida, 33321, United States
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West Palm Beach, Florida, 33401, United States
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Atlanta, Georgia, 30318, United States
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Macon, Georgia, 30318, United States
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Macon, Georgia, 31210, United States
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Carterville, Illinois, 62918, United States
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Indianapolis, Indiana, 46237, United States
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Waukee, Iowa, 50263, United States
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Lexington, Kentucky, 40503, United States

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Covington, Louisiana, 70433, United States
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Baltimore, Maryland, 21229, United States
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Boston, Massachusetts, 02215, United States
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Milton, Massachusetts, 02186, United States

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Worcester, Massachusetts, 01655, United States
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Detroit, Michigan, 48202, United States
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Lansing, Michigan, 48910, United States

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Minneapolis, Minnesota, 55455, United States
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Saint Louis Park, Minnesota, 55426, United States
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Saint Paul, Minnesota, 55101, United States
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Hattiesburg, Mississippi, 39401, United States
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Kansas City, Missouri, 64132, United States
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St Louis, Missouri, 63128, United States
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Lebanon, New Hampshire, 03756, United States
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Basking Ridge, New Jersey, 07920, United States
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Middletown, New Jersey, 07748, United States
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Montvale, New Jersey, 07645, United States
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Mullica Hill, New Jersey, 08062, United States
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New Brunswick, New Jersey, 08901, United States
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Glen Falls, New York, 12801, United States
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Harrison, New York, 10604, United States
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New York, New York, 10065, United States
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Syracuse, New York, 13210, United States
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Uniondale, New York, 11553, United States
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Chapel Hill, North Carolina, 27592, United States
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Columbus, Ohio, 43219, United States
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Oklahoma City, Oklahoma, 73102, United States
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Eugene, Oregon, 97401, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19111, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Nashville, Tennessee, 37235, United States
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Abilene, Texas, 79601, United States
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Austin, Texas, 78745, United States
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Dallas, Texas, 75246, United States
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Forth Worth, Texas, 76104, United States
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Houston, Texas, 77030, United States
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Tyler, Texas, 75708, United States
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Webster, Texas, 77598, United States
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Salt Lake City, Utah, 84106, United States
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Blacksburg, Virginia, 24060, United States
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Charlottesville, Virginia, 22908, United States
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Fairfax, Virginia, 22031, United States
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Richmond, Virginia, 23229, United States
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Richmond, Virginia, 23298, United States
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Seattle, Washington, 98109, United States
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Vancouver, Washington, 98684, United States
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Edmonton, Alberta, T6G 1Z2, Canada
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London, Ontario, N6A 5W9, Canada
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Montreal, Quebec, H3T 1E2, Canada
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Montreal, H3T 1E2, Canada
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Fuzhou, Fujian, China
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Guangzhou, Guangdong, China
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Haikou, Hainan, China
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Harbin, Heilongjiang, 150081, China
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Ganzhou, Jiangxi, China
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Nanchang, Jiangxi, China
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Tai’an, Shandong, China
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Weifang, Shandong, China
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Shanghai, Shanghai Municipality, China
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Kunming, Yunnan, China
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Hangzhou, Zhejiang, China
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Taizhou, Zhejiang, China
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Changchun, China
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Guangzhou, China
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Xi'an, China
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Nantes, Pays de Loire, 44277, France
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Brest, 29200, France
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Créteil, 94010, France
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Lyon, 69008, France
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Marseille, 13000, France
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Paris, 75020, France
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Rennes, 35033, France
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Villejuif, 94800, France
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Chemnitz, 91116, Germany
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Gauting, 82131, Germany
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Giesen, 35392, Germany
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Karlsruhe, 76137, Germany
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Minden, 32429, Germany
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Moers, 47441, Germany
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Möser, 47441, Germany
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Athens, 15562, Greece
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Rio, 26504, Greece
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Thessaloniki, 546 22, Greece

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Budapest, 01121, Hungary
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Kecskemét, 6000, Hungary
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Bari, 70124, Italy
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Milan, 20037, Italy
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Milan, 20141, Italy
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Orbassano, 10043, Italy
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Parma, 43126, Italy
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Roma, 00144, Italy
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Asahikawa, Hokkaido, 078-8510, Japan
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Nishinomiya, Hyōgo, 663-8501, Japan
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Matsusaka, Mie-ken, 515-8544, Japan
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Sendai, Miyagi, 980-8574, Japan
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Omura-shi, Nagasaki, 856-8562, Japan
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Hirakata, Osaka, 573-1191, Japan
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Osaka, Osaka, 541-8567, Japan

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Hidaka, Saitama, 350-1298, Japan
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Shimotsuke, Tochigi, 329-0498, Japan
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Bunkyō-Ku, Tokyo, 113-8677, Japan
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Koto-Ku, Tokyo, 135-8550, Japan
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Wakayama, Wakayama, 641-8510, Japan
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Kanazawa, 920-8641, Japan
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Kumamoto, 861-4193, Japan
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Kurume, 830-0011, Japan
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Nagoya, 460-0001, Japan
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Okayama, 700-8558, Japan
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Sakai, 591-8555, Japan
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Tokyo, 104-0045, Japan
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Guadalajara, 44670, Mexico
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Mexico City, 06700, Mexico
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Monterrey, 64710, Mexico
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Veracruz, 91900, Mexico
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Gdansk, 80214, Poland
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Lodz, 93338, Poland
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Lublin, 20064, Poland
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Poznan, 60-693, Poland
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Skorzewo, 60185, Poland
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Braga, 4710-243, Portugal
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Coimbra, 3020-479, Portugal
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Faro, 8000-386, Portugal
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Porto, 4099-001, Portugal
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Suceagu, Cluj, 407062, Romania
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Baia Mare, 430031, Romania
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Bucharest, 22328, Romania
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Cluj-Napoca, 407062, Romania
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Cluj-Napoca, 407280, Romania
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Craiova, 200542, Romania
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Iași, 700106, Romania
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Ovidiu, 905900, Romania
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Timișoara, 300166, Romania
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Belgrade, 11040, Serbia
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Belgrade, 11080, Serbia
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Kragujevac, 34000, Serbia
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Novi Sad, 21204, Serbia
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Badajoz, 06080, Spain
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Badalona, 08916, Spain
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Barcelona, 08003, Spain
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Girona, 17007, Spain
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Las Palmas, 35016, Spain
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Lugo, 27002, Spain
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Madrid, 28040, Spain
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Málaga, 29011, Spain
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Seville, 41014, Spain
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Valencia, 46026, Spain
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Zaragoza, 50009, Spain
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Adana, 01140, Turkey (Türkiye)
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Ankara, 06520, Turkey (Türkiye)
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Antalya, 07059, Turkey (Türkiye)
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Diyarbakır, 21280, Turkey (Türkiye)
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Gaziantep, 27060, Turkey (Türkiye)
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Istanbul, 34460, Turkey (Türkiye)
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Istanbul, 34722, Turkey (Türkiye)

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İzmit, 41380, Turkey (Türkiye)
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Konya, 42080, Turkey (Türkiye)
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Seyhan, 07059, Turkey (Türkiye)
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Detroit, Michigan, 48202, United States
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Lebanon, Ohio, 45036, United States

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CANCER