Global trial aims to boost survival for lung cancer patients

NCT ID NCT06712316

Recruiting now Disease control Sponsor: BioNTech SE Source: ClinicalTrials.gov ↗

Summary

This global study is testing whether adding an investigational drug called BNT327 to standard chemotherapy works better for people with advanced non-small cell lung cancer who haven't had prior treatment. The trial will enroll about 1,260 participants across multiple sites to compare the safety and effectiveness of the new combination against current standard care. Researchers will measure how long patients live without their cancer getting worse and monitor side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Acibadem Adana Hospital
RECRUITING

Seyhan, 01130, Turkey (Türkiye)
Adana City Training and Research Hospital
RECRUITING

Adana, 1370, Turkey (Türkiye)
Affiliated Hospital of Hebei University
RECRUITING

Baoding, 071000, China
Ageo Central General Hospital
RECRUITING

Ageo, 362-8588, Japan
Ajou University Hospital
RECRUITING

Suwon, 16499, South Korea
Akdeniz University Hospital
RECRUITING

Antalya, 7985, Turkey (Türkiye)
Alaska Oncology and Hematology, LLC
RECRUITING

Anchorage, Alaska, 99508, United States
Ankara Bilkent City Hospital
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Asan Medical Center (AMC)
RECRUITING

Seoul, 05505, South Korea
Asklepios Fachkliniken Muenchen Gauting
RECRUITING

Gauting, 82131, Germany
Astera Cancer Care
RECRUITING

East Brunswick, New Jersey, 08816, United States
Azienda Ospedaliera San Giuseppe Moscati
RECRUITING

Avellino, 83100, Italy
Azienda Ospedaliero Universitaria Di Bologna Policlinico S. Orsola Malpighi
RECRUITING

Bologna, 40138, Italy
Azienda Socio Sanitaria Territoriale di Cremona (ASST Cremona)
RECRUITING

Cremona, 26100, Italy
Baptist Cancer Center
RECRUITING

Memphis, Tennessee, 38120, United States
Baptist Health Hardin
RECRUITING

Elizabethtown, Kentucky, 42701, United States
Baskent Universitesi Tip Fakultesi Adana Hastanesi
RECRUITING

Adana, 1120, Turkey (Türkiye)
Beatson West of Scotland Cancer Centre - Greater Glasgow Health Board
RECRUITING

Glasgow, G12 0YN, United Kingdom
Beijing Friendship Hospital, Capital Medical University
RECRUITING

Beijing, 100050, China
Bezmialem Foundation University Medical Faculty
RECRUITING

Istanbul, 34093, Turkey (Türkiye)
CHU Caen Normandie
RECRUITING

Caen, 14033, France
CHU HELORA, Hopital de Mons - Site Kennedy
RECRUITING

Mons, 7000, Belgium
CHU de Rennes, Hopital de Pontchaillou
RECRUITING

Rennes, 35033, France
Cairns Hospital
RECRUITING

Cairns, 4870, Australia
Cancer And Haematology Centre-The Churchill Hospital-Oxford University Hospitals
RECRUITING

Oxford, OX3 7LJ, United Kingdom
Cancer Care Wollongong Pty Limited
RECRUITING

Wollongong, 2500, Australia
Cancer Hospital of Shantou University Medical College
RECRUITING

Shantou, 515041, China
Cancer Research SA (CRSA)
RECRUITING

Adelaide, 5000, Australia
Cardiomed
RECRUITING

Cluj-Napoca, 400015, Romania
Casa Di Cura Polispecialistica Dott Pederzoli
RECRUITING

Peschiera del Garda, 37019, Italy
Central West Cancer Care Centre
RECRUITING

Orange, 2800, Australia
Centre Francois Baclesse
RECRUITING

Caen, 14076, France
Centre Hospitalier Intercommunal Toulon La Seyne Sur Mer (C.H.I.T.S) - Hospital Font-Pre
RECRUITING

Toulon, 83000, France
Centre Hospitalier Intercommunal de Creteil (CHIC) - Centre de ressources et de competences pour la mucoviscidose (C.R.C.M.)
RECRUITING

Créteil, 94010, France
Centre Hospitalier Universitaire d'Angers (CHU Angers)
RECRUITING

Angers, 49933, France
Centro di Riferimento Oncologico
RECRUITING

Aviano, 33081, Italy
Centrul de Oncologie Sf. Nectarie S.R.L (Sf Nectarie Oncology Center)
RECRUITING

Craiova, 200542, Romania
Chiangrai Prachanukroh Hospital
RECRUITING

Chiang Rai, 57000, Thailand
Chongqing University Three Gorges Hospital
RECRUITING

Wanzhou, 404000, China
Chulalongkorn University
RECRUITING

Bangkok, 10330, Thailand
Chungbuk National University Hospital
RECRUITING

Cheongju-si, 28644, South Korea
Chungnam National University Hospital (CNUH)
RECRUITING

Daejeon, 35015, South Korea
Clatterbridge Cancer Centre
RECRUITING

Liverpool, L7 8YA, United Kingdom
Clermont Oncology Center
RECRUITING

Clermont, Florida, 34711, United States
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195-0001, United States
Cleveland Clinic - Hillcrest Hospital
RECRUITING

Mayfield Heights, Ohio, 44124, United States
Cleveland Clinic Florida - Martin North Hospital
RECRUITING

Stuart, Florida, 34994, United States
Cleveland Clinic Weston Hospital
RECRUITING

Weston, Florida, 33331, United States
Clinica MD Anderson International
RECRUITING

Madrid, 28033, Spain
Coltea Clinical Hospital
RECRUITING

Bucharest, 030171, Romania
Complejo Hospitalario Universitario Insular Materno Infantil
RECRUITING

Las Palmas de Gran Canaria, 35016, Spain
Consorcio Hospitalario Provincial de Castellón
RECRUITING

Castellon, 12002, Spain
Dicle University Faculty of Medicine Hospital
RECRUITING

Diyarbakır, 21280, Turkey (Türkiye)
Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
RECRUITING

Ankara, 06200, Turkey (Türkiye)
Dubbo Hospital
RECRUITING

Dubbo, 2830, Australia
Evangelische Lungenklinik Berlin
RECRUITING

Berlin, 13125, Germany
Faculty of Medicine Vajira Hospital, Navamindradhiraj University
RECRUITING

Bangkok, 10300, Thailand
Fletcher Hospital, Inc. dba AdventHealth Hendersonville
RECRUITING

Hendersonville, North Carolina, 28792, United States
Flinders Medical Centre
RECRUITING

Bedford Park, 5042, Australia
Fondazione Ospedale Isola Tiberina - Gemelli Isola
RECRUITING

Rome, 00186, Italy
Fondazione Policlinico Universitario Campus Bio-Medico
RECRUITING

Roma, 00128, Italy
Frederick Health Hospital- James M Stockman Cancer Institute
RECRUITING

Frederick, Maryland, 21704, United States
Fundacion Instituto Valenciano de Oncologia
RECRUITING

Valencia, 46009, Spain
Gabrail Cancer Center Research
RECRUITING

Canton, Ohio, 44718, United States
Gachon University Gil Medical Center
RECRUITING

Incheon, 21565, South Korea
Gazi University Faculty of Medicine
RECRUITING

Yenimahalle, 06560, Turkey (Türkiye)
Gaziantep Sanko University Medical Faculty
RECRUITING

Gaziantep, 36020, Turkey (Türkiye)
Goztepe Prof. Dr. Suleyman Yalcin City Hospital
RECRUITING

Kadıköy, 34722, Turkey (Türkiye)
Gulhane Training and Research Hospital
RECRUITING

Ankara, 06010, Turkey (Türkiye)
Gyeongsang National University Hospital (GNUH)
RECRUITING

Jinju, 52727, South Korea
H. Lee Moffit Cancer center and research institute
RECRUITING

Tampa, Florida, 33612, United States
HRH Princess MahaChakri Sirindhorn Medical Center - Srinakharinwirot University
RECRUITING

Nakhon Nayok, 26120, Thailand
Hacettepe University Medicine Faculty
RECRUITING

Ankara, 06230, Turkey (Türkiye)
Helios Klinikum Wuppertal-Universitaet Witten-Herdecke
RECRUITING

Wuppertal, 42883, Germany
Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States
Hospital Alvaro Cunqueiro
RECRUITING

Vigo, 36312, Spain
Hospital General Universitario De Valencia
RECRUITING

Valencia, 46014, Spain
Hospital General Universitario Gregorio Maranon (HGUGM)
RECRUITING

Madrid, 28007, Spain
Hospital Universitari de Lleida Arnau de Villanova
RECRUITING

Lleida, 25198, Spain
Hospital Universitario De Leon
RECRUITING

León, 24080, Spain
Hospital Universitario Fundacion Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
Hospital Universitario Miguel Servet de Zaragoza
RECRUITING

Zaragoza, 50009, Spain
Hospital Universitario Nuestra Senora De Valme
RECRUITING

Seville, 41014, Spain
Hospital Universitario Puerta de Hierro de Majadahonda
RECRUITING

Majadahonda, 28222, Spain
Hospital Universitario Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, 41013, Spain
Hospital Universitario de Badajoz
RECRUITING

Badajoz, 6006, Spain
Hospital Universitario de Canarias
RECRUITING

Santa Cruz de Tenerife, 38320, Spain
Hull University Teaching Hospitals NHS Trust
RECRUITING

Cottingham, HU16 5JQ, United Kingdom
ICON Cancer Care - Townsville
RECRUITING

Townsville, 4812, Australia
INTEGRIS Cancer Institute of Oklahoma
RECRUITING

Oklahoma City, Oklahoma, 73109, United States
IRCCS Istituto Romagnolo per lo studio dei Tumori Dino Amadori (IRST)
RECRUITING

Meldola, 47014, Italy
Icon Cancer Centre Kurralta Park
RECRUITING

Kurralta Park, 5037, Australia
Institut Bergonie - Centre Regional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest
RECRUITING

Bordeaux, 33076, France
Institut Catala d'Oncologia Badalona, Hospital Germans Trias I Pujol
RECRUITING

Badalona, 08916, Spain
Institut Curie - Centre de Recherche
RECRUITING

Paris, 75005, France
Institut Gustave Roussy-Gustave Roussy Cancer Center -DITEP
RECRUITING

Villejuif, 94805, France
Institut Paoli-Calmettes
RECRUITING

Marseille, 13009, France
Institut de Cancerologie de l'Ouest (ICO)- CRLCC Rene Gauducheau
RECRUITING

Saint-Herblain, 44805, France
Instytut MSF Sp. z o.o.
RECRUITING

Lodz, 90-302, Poland
Istinye University Bahcesehir Liv Hospital
RECRUITING

Istanbul, 34517, Turkey (Türkiye)
Istituti di Ricovero e Cura A Carattere Scientifico (IRCCS) - Istituti Fisioterapici Ospitalieri (IFO) - Istituto Nazionale Tumori Regina Elena (IRE)
RECRUITING

Roma, 00144, Italy
Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele (HSR) (Istituto Scientifico Universitario San Raffaele)
RECRUITING

Milan, 20132, Italy
Iwate Medical University Hospital
RECRUITING

Morioka, 028-3695, Japan
Jiangsu Peoples Hospital
RECRUITING

Nanjing, 210029, China
Jilin Cancer Hospital
RECRUITING

Changchun, 130000, China
John Muir Clinical Research Center
RECRUITING

Concord, California, 94520, United States
Karadeniz Technical University Faculty of Medicine
RECRUITING

Ortahisar, 61080, Turkey (Türkiye)
Kettering Medical Center
RECRUITING

Kettering, Ohio, 45429, United States
Klinikum Chemnitz gGmbH
RECRUITING

Chemnitz, 09116, Germany
Klinikum Esslingen GmbH
RECRUITING

Esslingen am Neckar, 73730, Germany
Koc Universitesi Hastanesi (Koc University Hospital)
RECRUITING

Zeytinburnu, 34010, Turkey (Türkiye)
Kocaeli Universitesi Tip Fakultesi
RECRUITING

Kocaeli, 41380, Turkey (Türkiye)
Korea University Guro Hospital
RECRUITING

Seoul, 08308, South Korea
Lampang Cancer Hospital
RECRUITING

Lampang, 52000, Thailand
Liv Hospital Ankara
RECRUITING

Ankara, 06680, Turkey (Türkiye)
Lungenfachklinik Immenhausen - Pneumologische Lehrklinik der Universitaet Goettingen
RECRUITING

Immenhausen, 34376, Germany
MVZ for oncology and hematology Rhein-Kreis Neuss GmbH
RECRUITING

Neuss, 41462, Germany
Mary Lanning Healthcare (MLH) - Morrison Cancer Center (MCC)
RECRUITING

Hastings, Nebraska, 68901-4470, United States
Matsusaka Municipal Hospital
RECRUITING

Matsusaka, 515-8544, Japan
Medical Park Florya Hospital
RECRUITING

Küçükçekmece, 34295, Turkey (Türkiye)
Medical Park Seyhan Hospital
RECRUITING

Seyhan, 01170, Turkey (Türkiye)
Medical Point Izmir Hospital
RECRUITING

Izmir, 35325, Turkey (Türkiye)
Memorial Ankara Hospital
RECRUITING

Ankara, 06520, Turkey (Türkiye)
Mersin City Training and Research Hospital
RECRUITING

Toroslar, 33240, Turkey (Türkiye)
Millennium Research and Clinical Development, LLC
ACTIVE_NOT_RECRUITING

Houston, Texas, 77090, United States
Monash University - Monash Health -Monash Medical Centre
RECRUITING

Melbourne, 3168, Australia
Municipal Hospital Ploiesti
RECRUITING

Ploieşti, 100337, Romania
NHO Kinki Chuo Chest Medical Center
RECRUITING

Sakai, 591-8555, Japan
NZOZ Medpolonia Sp. Z o.o.
RECRUITING

Poznan, 60-693, Poland
Nagoya University Hospital
RECRUITING

Nagoya, 466-8560, Japan
National Cancer Center
RECRUITING

Goyang-si, 10408, South Korea
National Hospital Organization Himeji Medical Center
RECRUITING

Himeji, 670-8520, Japan
National Hospital Organization Iwakuni Clinical Center
RECRUITING

Iwakuni, 740-8510, Japan
National Hospital Organization Nagoya Medical Center
RECRUITING

Nagoya, 460-0001, Japan
National Hospital Organization Shikoku Cancer Center
RECRUITING

Matsuyama, 791-0280, Japan
National Hospital Organization Tokyo Medical Center
RECRUITING

Meguro City, 152-8902, Japan
New Cross Hospital
RECRUITING

Wolverhampton, WV10 0QP, United Kingdom
Niigata Cancer Center Hospital
RECRUITING

Niigata, 951-8566, Japan
Norfolk and Norwich University Hospital - Norfolk and Norwich University Hospitals NHS Foundation Trust
RECRUITING

Norwich, NR4 7UY, United Kingdom
Northern Jiangsu Peoples Hospital (NJPH)
RECRUITING

Yangzhou, 225001, China
Onco Clinic Consult SA
RECRUITING

Craiova, 200094, Romania
Oncomed
RECRUITING

Timișoara, 300239, Romania
Ondokuz Mayis University Health Practice and Research Hospital
RECRUITING

Samsun, 55280, Turkey (Türkiye)
Onkologische Tagesklinik Remscheid
RECRUITING

Remscheid, 42853, Germany
Osaka Prefectural Hospital Organization Osaka International Cancer Institute
RECRUITING

Osaka, 541-8567, Japan
Ospedale San Luca
RECRUITING

Lucca, 55100, Italy
Ovidius Clinical Hospital
RECRUITING

Ovidiu, 905900, Romania
Peninsula & South Eastern Haematology and Oncology Group
RECRUITING

Frankston, 3199, Australia
Peter MacCallum Cancer Centre
RECRUITING

Melbourne, 3000, Australia
Physicians Clinic of Iowa
RECRUITING

Cedar Rapids, Iowa, 52401-2112, United States
Praxiskooperation Bonn-Euskirchen-Rheinbach-Wesseling
RECRUITING

Wesseling, 50389, Germany
Radiotherapy Center Cluj
RECRUITING

Cluj-Napoca, 407280, Romania
Rajavithi Hospital
RECRUITING

Ratchathewi, 10400, Thailand
Royal Adelaide Hospital
RECRUITING

Adelaide, 5000, Australia
Royal Marsden Hospital (RMH) - Royal Marsden NHS Foundation Trust
RECRUITING

Chelsea, SW3 6JJ, United Kingdom
Royal Marsden Hospital (Sutton) - Royal Marsden NHS Foundation Trust
RECRUITING

London, SM2 5PT, United Kingdom
Royal Preston Hospital - Lancashire Teaching Hospitals NHS Foundation Trust
RECRUITING

Preston, PR2 9HT, United Kingdom
Royal Sussex County Hospital - University Hospitals Sussex NHS Foundation Trust
RECRUITING

Brighton, BN2 5BE, United Kingdom
S.C. Medisprof S.R.L, Oncologie medicala
RECRUITING

Cluj-Napoca, 400641, Romania
SC Gral Medical SRL
RECRUITING

Bucharest, 031424, Romania
SRH Wald-Kliniken Gera GmbH
RECRUITING

Gera, 07548, Germany
SSM Health Cancer Care - St. Clare
RECRUITING

Fenton, Missouri, 63026, United States
Sakarya University - Faculty of Medicine
RECRUITING

Sakarya, 54290, Turkey (Türkiye)
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Sendai Kousei Hospital
RECRUITING

Sendai, 981-0914, Japan
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Shandong University - Jinan Central Hospital
RECRUITING

Jinan, 250013, China
Shanghai Chest Hospital
RECRUITING

Shanghai, 200030, China
Shizuoka Cancer Center
RECRUITING

Nagaizumi-chō, 411-8777, Japan
Southampton General Hospital
RECRUITING

Southampton, SO16 6YD, United Kingdom
Summit Medical Group PA
RECRUITING

Florham Park, New Jersey, 07932, United States
Suny-Stony Brook University Cancer Center
RECRUITING

Stony Brook, New York, 11794-9446, United States
Taizhou Hospital of Zhejiang Province
RECRUITING

Zhejiang, 317000, China
The Catholic University Of Korea, St. Vincent's Hospital
RECRUITING

Suwon, 16247, South Korea
The Christ Hospital Cancer Center
RECRUITING

Cincinnati, Ohio, 45219, United States
The Christie NHS Foundation Trust
RECRUITING

Manchester, M20 4BX, United Kingdom
The Cleveland Clinic Cancer Center At Fairview Hospital, Moll Pavilion
RECRUITING

Cleveland, Ohio, 44111, United States
The First Affiliated Hospital of Soochow University
RECRUITING

Suzhou, 215006, China
The Valley Hospital - Valley Health System - The Robert and Audrey Luckow Pavilion
RECRUITING

Paramus, New Jersey, 07652, United States
Thoraxklinik-Heidelberg Ggmbh
RECRUITING

Heidelberg, 69126, Germany
Tokyo Metropolitan Komagome Hospital
RECRUITING

Bunkyō City, 113-8677, Japan
UOC Oncoematologia AOU Luigi Vanvitelli
RECRUITING

Naples, 80131, Italy
Uniklinik RWTH Aachen Medizinische Klinik IV
RECRUITING

Aachen, 52074, Germany
Universita di Siena -Azienda Ospedaliera Universitaria Senese-Policlincio Santa Maria Alle Scotte
RECRUITING

Siena, 53100, Italy
Universitair Ziekenhuis Leuven
RECRUITING

Leuven, 3000, Belgium
Universitat de Valencia - Hospital Universitari i Politecnic La Fe de Valencia (Hospital La Fe Bulevar Sur)
RECRUITING

Valencia, 46026, Spain
University College Hospital
RECRUITING

London, NW2 1PG, United Kingdom
University Medical Center of Johannes Gutenberg-University Mainz
RECRUITING

Mainz, 55131, Germany
University Of California - San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States
University of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Tennessee Medical Center
RECRUITING

Knoxville, Tennessee, 37920, United States
Universitätsklinikum Erlangen
RECRUITING

Erlangen, 91054, Germany
Uniwersyteckie Centrum Kliniczne (UCK) - Klinika Onkologii i Radioterapii
RECRUITING

Gdansk, 80-211, Poland
VCU Massey Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States
VITAZ
RECRUITING

Sint-Niklaas, 9100, Belgium
Velindre NHS Trust, Velindre Cancer Centre
RECRUITING

Cardiff, CF14 2TL, United Kingdom
Virginia Cancer Specialists
RECRUITING

Fairfax, Virginia, 22031, United States
Wakayama Medical University Hospital
RECRUITING

Wakayama, 641-8510, Japan
Western Health Sunshine Hospital
RECRUITING

St Albans, 3021, Australia
White Plains Hospital
RECRUITING

White Plains, New York, 10601, United States
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu
RECRUITING

Przemyśl, 37-700, Poland
Yeditepe University Kosuyolu Hospital
RECRUITING

Istanbul, 34718, Turkey (Türkiye)
Yunnan Provincial Cancer Hospital
RECRUITING

Kunming, 650118, China
Zhejiang Medical University, Zhejiang Cancer Hospital
RECRUITING

Hangzhou, 310022, China
Zhongnan Hospital of Wuhan University
RECRUITING

Wuhan, 430071, China

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CANCER