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New hope for lung cancer patients when standard drugs stop working

NCT ID NCT05601973

Ongoing Disease control Sponsor: ETOP IBCSG Partners Foundation Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding two drugs (amivantamab and bevacizumab) to a continued targeted therapy (lazertinib) can help control advanced lung cancer that has started growing again after previous treatment. It will involve about 60 patients with a specific genetic change (EGFR mutation) in their cancer. The main goal is to see if this three-drug combination can shrink tumors and provide data for a larger future study.

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Contacts and locations

Locations

  • AO SM Misericorida Perugia

    Perugia, Italy

  • Catalan Institute of Oncology

    L'Hospitalet de Llobregat, Spain

  • Centre Hospitalier d'Avignon

    Avignon, France

  • Centre Léon Bérard

    Lyon, France

  • Chu Angers

    Angers, France

  • Hospital Universitario Alicante Dr Balmis ISABIAL

    Alicante, Spain

  • Hospital Universitario Basurto

    Bilbao, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, Spain

  • Hospital Universitario de A Coruña

    A Coruña, Spain

  • Hospital clínico universitario de Valladolid

    Valladolid, Spain

  • Hôpitaux universitaires de Genève (HUG)

    Geneva, Switzerland

  • ICO Badalona

    Badalona, Spain

  • Istituto Oncologico della Svizzera Italiana

    Bellinzona, Switzerland

  • Kantonsspital St. Gallen

    Sankt Gallen, Switzerland

  • Netherlands Cancer Institute (NKI)

    Amsterdam, Netherlands

  • The Royal Marsden NHS Foundation Trust

    London, United Kingdom

  • Universitätsklinik für Medizinische Onkologie, Inselspital

    Bern, Switzerland

  • Vall d´Hebron University Hospital VHIO

    Barcelona, Spain

Conditions

Explore the condition pages connected to this study.

NON-SMALL CELL LUNG CANCER