New drug shows promise in protecting patients during aggressive lung cancer treatment

NCT ID NCT03041311

Completed Disease control Sponsor: G1 Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested if adding a new drug called trilaciclib to standard chemotherapy and immunotherapy could better control advanced small cell lung cancer. The main goal was to see if trilaciclib could protect patients' bone marrow and immune system from the harsh side effects of treatment, potentially allowing them to stay on therapy longer. About 100 patients with newly diagnosed, advanced disease were randomly assigned to receive the standard treatment with or without trilaciclib.

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Contacts and locations

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Locations

Beverly Hills Cancer Center

Beverly Hills, California, 90211, United States
Blue Ridge Cancer Care

Blacksburg, Virginia, 24060, United States
CHU Caen De La Côte De Nacre

Caen, 14033, France
Centre Oscar Lambret

Lille, 59020, France
Chernivtsi Regional Clinical Oncology Center

Chernivtsi, 58013, Ukraine
Complex Oncology Center - Burgas

Burgas, 8000, Bulgaria
Daugavpils Regional Hospital, Department of Oncology

Daugavpils, LV-5417, Latvia
Dnipropetrovsk City Multispecialty Clinical Hospital #4

Dnipro, 49102, Ukraine
East Tallinn Central Hospital Ltd., Clinic of Internal Medicine, Center for Oncology

Tallinn, 11312, Estonia
Fort Belvoir Community Hospital

Fort Belvoir, Virginia, 22060, United States
Gibbs Cancer Center

Spartanburg, South Carolina, 29303, United States
H. Donostia, Hospital Donostia- Servicio de Oncología

San Sebastián, 20014, Spain
H.U. Quirón Dexeus, Hospital Universitario

Barcelona, 08028, Spain
Horizon Oncology Center

Lafayette, Indiana, 47905, United States
Hospital 12 de Octubre

Madrid, 28041, Spain
Hospital Arnau de Vilanova

Valencia, 46015, Spain
Hospital Clinic de Barcelona- Servicio de Oncología Médica

Barcelona, 08036, Spain
Hospital Clínico

San Carlos, Madrid, 28040, Spain
Hospital Teresa Herrera

A Coruña, La Coruña, 15006, Spain
Hospital Universitario Ntra. Sra. de Valme

Seville, 41014, Spain
Hospital Universitario Puerta de Hierro Majadahonda

Majadahonda, Madrid, 28222, Spain
Hospital Universitario Ramón y Cajal

Madrid, 28034, Spain
Hospital Universitario Son Espases

Palma, Balearic Islands, 07120, Spain
Joliet Oncology-Hematology Associates

Joliet, Illinois, 60435, United States
Loma Linda University

Loma Linda, California, 92350, United States
Lviv State Regional Treatment and Diagnostics Oncology Center

Lviv, 79031, Ukraine
Millennium Oncology

Houston, Texas, 77090, United States
Multiprofile Hospital for Active Treatment "Serdika"

Sofia, 1303, Bulgaria
Multiprofile Hospital for Active Treatment "Serdika", Sofia

Sofia, 1303, Bulgaria
Northern Westchester Hospital

Mount Kisco, New York, 10549, United States
Northside Hospital - Georgia Cancer Specialists

Atlanta, Georgia, 30341, United States
Ochsner Clinic Foundation

New Orleans, Louisiana, 70121, United States
Oklahoma University - Peggy and Charles Stephenson Cancer Center

Oklahoma City, Oklahoma, 73117, United States
Pauls Stradiņš Clinical University Hospital, Oncology Clinic

Riga, LV-1002, Latvia
Piedmont Cancer Institute

Atlanta, Georgia, 30318, United States
Redwood Regional Medical Group (RRMG) - Fountain Grove

Santa Rosa, California, 95403, United States
Singing River Health System

Whittier, California, 90603, United States
St. Jude Heritage Healthcare

Fullerton, California, 92835, United States
St. Louis Cancer Care, LLP, North County

Bridgeton, Missouri, 63044, United States
Summit Medical Group, P.A.

Morristown, New Jersey, 07962, United States
The Alvin J. Siteman Cancer Center - Center for Advanced Med

St Louis, Missouri, 63110-1094, United States
Trinity Health - Trinity CancerCare Center

Minot, North Dakota, 58701, United States
UCLA Medical Center - Santa Monica Hematology And Oncology

Santa Monica, California, 90404, United States
Valley Cancer Associates

Harlingen, Texas, 78550, United States
Virginia Cancer Specialists

Arlington, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.

SMALL CELL LUNG CANCER