New hope for lung cancer patients: major trial tests powerful drug combo before surgery

NCT ID NCT04379635

Summary

This study is testing whether adding an immunotherapy drug called tislelizumab to standard chemotherapy, given both before and after surgery, works better than chemotherapy alone for people with early-stage non-small cell lung cancer. The goal is to shrink the tumor before surgery and prevent the cancer from coming back afterward. About 453 participants with stage II or IIIA lung cancer who are eligible for surgery will be randomly assigned to receive either the real drug or a placebo alongside their chemotherapy.

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Contacts and locations

Locations

  • Affiliated Zhongshan Hospital of Fudan University

    Shanghai, Shanghai Municipality, 200032, China

  • Anhui Provincial Hospital

    Hefei, Anhui, 230000, China

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100050, China

  • Beijing Hospital

    Beijing, Beijing Municipality, 100730, China

  • Cancer Center of Guangzhou Medical University

    Guangzhou, Guangdong, 510030, China

  • Cancer Hospital of Shantou University Medical College

    Shantou, Guangdong, 515031, China

  • First Hospital of Shanxi Medical University

    Taiyuan, Shanxi, 030000, China

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200000, China

  • Fujian Cancer Hospital

    Fuzhou, Fujian, 350014, China

  • Fujian Medical University Union Hospital

    Fuzhou, Fujian, 350001, China

  • General Hospital of Ningxia Medical University

    Yinchuan, Ningxia, 750004, China

  • Hainan Cancer Hospital

    Haikou, Hainan, 570312, China

  • Harbin Medical University Cancer Hospital

    Harbin, Heilongjiang, 150000, China

  • Hubei Cancer Hospital

    Wuhan, Hubei, 430079, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410013, China

  • Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No2 Hospital)

    Ningbo, Zhejiang, 315000, China

  • Jiangmen Central Hospital

    Jiangmen, Guangdong, 529030, China

  • Jilin Cancer Hospital

    Changchun, Jilin, 130021, China

  • Liaoning Cancer Hospital and Institute

    Shenyang, Liaoning, 110042, China

  • Luoyang Central Hospital

    Luoyang, Henan, 471009, China

  • Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School

    Nanjing, Jiangsu, 210008, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100730, China

  • Peking University Peoples Hospital

    Beijing, Beijing Municipality, 100044, China

  • Quanzhou First Affliated Hospital of Fujian Medical University

    Quanzhou, Fujian, 362000, China

  • Shanghai Chest Hospital

    Shanghai, Shanghai Municipality, 200030, China

  • Shanghai Pulmonary Hospital

    Shanghai, Shanghai Municipality, 200433, China

  • Sichuan Cancer Hospital and Institute

    Chengdu, Sichuan, 610041, China

  • Sun Yat Sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • The First Affiliated Hospital of Nanchang University Branch Donghu

    Nanchang, Jiangxi, 330006, China

  • The First Affiliated Hospital of Nanchang University Branch Xianghu

    Nanchang, Jiangxi, 332000, China

  • The First Affiliated Hospital of Xiamen University

    Xiamen, Fujian, 361003, China

  • The First Affiliated Hospital of Xian Jiaotong University

    Xi'an, Shaanxi, 710061, China

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310003, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310009, China

  • The Tumor Hospital Affiliated to Guangxi Medical University

    Nanning, Guangxi, 530021, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • Tianjin Medical University General Hospital

    Tianjin, Tianjin Municipality, 300052, China

  • Union Hospital of Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610041, China

  • Xuanwu Hospital Capital Medical University

    Beijing, Beijing Municipality, 100053, China

  • Yunnan Cancer Hospital

    Kunming, Yunnan, 650100, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

Conditions

Explore the condition pages connected to this study.