Personalized vaccine plus immunotherapy aims to stop lung cancer recurrence
NCT ID NCT07513376
First seen Apr 23, 2026 · Last updated May 16, 2026 · Updated 6 times
Summary
This study tests whether a personalized cancer vaccine (intismeran) alone or combined with an immunotherapy (pembrolizumab) can prevent non-small cell lung cancer from returning after surgery. About 876 adults with high-risk stage I lung cancer that was fully removed will be randomly assigned to receive the vaccine, the vaccine plus immunotherapy, or a placebo. The goal is to see if these treatments improve how long people stay cancer-free.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Altru Health System ( Site 3254)
RECRUITINGGrand Forks, North Dakota, 58201, United States
Contact Phone: •••-•••-••••
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Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 2503)
RECRUITINGKingston, Ontario, K7L 2V7, Canada
Contact Phone: •••-•••-••••
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NHO Revive Research Institute, LLC ( Site 3218)
RECRUITINGLincoln, Nebraska, 68506, United States
Contact Phone: •••-•••-••••
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One Clinical Research ( Site 0501)
RECRUITINGNedlands, Western Australia, 6009, Australia
Contact Phone: •••-•••-••••
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Renown Regional Medical Center-Renown Health Medical Oncology ( Site 3207)
RECRUITINGReno, Nevada, 89502, United States
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.