New drug shields patients from harsh chemo side effects

NCT ID NCT02514447

Completed Disease control Sponsor: G1 Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether a new drug called trilaciclib could protect the bone marrow and immune system in people with advanced small cell lung cancer who were receiving chemotherapy (topotecan). The main goal was to see if trilaciclib could reduce severe drops in white blood cell counts, a common and dangerous side effect of chemo. About 123 patients who had been treated before participated in this early-stage trial.

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Contacts and locations

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Locations

AZ Klina

Brasschaat, 2930, Belgium
AnMed Health

Anderson, South Carolina, 29621, United States
Clinic for Pulmology, Clinical Centre of Serbia

Belgrade, 11000, Serbia
Clinical Center Nis, Clinic for Lung Diseases

Niš, 18204, Serbia
Clinical Hospital Centre Bezanijska Kosa

Belgrade, 11000, Serbia
Clinical Hospital Centre Osijek

Osijek, 31000, Croatia
Compassionate Cancer Care Medical Group, Inc.

Corona, California, 92879, United States
Emory University

Atlanta, Georgia, 30322, United States
Florida Cancer Specialists - North

Tavares, Florida, 32778, United States
Florida Cancer Specialists - South

Fort Myers, Florida, 33916, United States
Gabrail Cancer Center

Canton, Ohio, 44718, United States
Genesis Cancer Center

Hot Springs, Arkansas, 71913, United States
Gibbs Cancer Center

Spartanburg, South Carolina, 29303, United States
Greenville Health System

Greenville, South Carolina, 29605, United States
Guthrie Medical Group, PC

Sayre, Pennsylvania, 18840, United States
Hanna Cancer Associates - University of Tennessee

Knoxville, Tennessee, 37920, United States
Highlands Oncology Group

Rogers, Arkansas, 72758, United States
Institute for Pulmonary Diseases of Vojvodina Clinic for Thoracic Oncology

Kamenitz, 21204, Serbia
M.D. Anderson

Houston, Texas, 77030, United States
Meharry Medical College

Nashville, Tennessee, 37208, United States
Memorial Hospital - University of Colorado Health

Colorado Springs, Colorado, 80909, United States
Millennium Oncology

Houston, Texas, 77090, United States
Norris Cotton Cancer Center

Lebanon, New Hampshire, 03756, United States
North Shore Hematology Oncology Associates PC

East Setauket, New York, 11733, United States
Northside Hospital - Georgia Cancer Specialists

Atlanta, Georgia, 30341, United States
Northwest Cancer Specialists, P.C.

Vancouver, Washington, 98684, United States
Oklahoma University - Peggy and Charles Stephenson Cancer Center

Oklahoma City, Oklahoma, 73117, United States
Oncology and Radiology Institute of Serbia

Belgrade, 11000, Serbia
POKO POPRAD, s.r.o.

Poprad, 05801, Slovakia
Regional Medical Oncology Center

Wilson, North Carolina, 27893, United States
Rocky Mountain Cancer Centers

Denver, Colorado, 80218, United States
Saint Luke's Cancer Institute

Kansas City, Missouri, 64111, United States
Sarah Cannon Research Institute

Nashville, Tennessee, 37232, United States
Southwest Cancer Center

Lubbock, Texas, 79415, United States
Sutter Medical Group

Sacramento, California, 95816, United States
Texas Oncology

Tyler, Texas, 75702, United States
Texas Oncology- Baylor Charles A. Sammons Cancer Center

Dallas, Texas, 75246, United States
The Oncology Institute of Hope and Innovation

Whittier, California, 90603, United States
The University of Texas Health Science Center at Tyler

Tyler, Texas, 75708, United States
University Cancer and Blood Center, LLC

Athens, Georgia, 30607, United States
University Clinic of Radiotherapy and Oncology Skopje

Skopje, 1000, North Macedonia
University Clinic of Respiratory and Allergic Diseases Golnik

Golnik, Slovenia
University Clinical Centre Banja Luka

Banja Luka, 78000, Bosnia and Herzegovina
University Clinical Centre Sarajevo

Sarajevo, 71000, Bosnia and Herzegovina
University Clinical Hospital Centre " Sestre Milosrdnice"

Zagreb, 10000, Croatia
University Hospital Centre Zagreb, Clinic For Pulmonary Diseases Jordanovac

Zagreb, 10000, Croatia
University of Colorado Health, Oncology Clinical Research Northern Region

Fort Collins, Colorado, 80528, United States
VOU Department of Radiotherapy and Oncology

Košice, 04191, Slovakia
Virginia Cancer Specialists

Fairfax, Virginia, 22031, United States
Virginia Oncology Associates

Norfolk, Virginia, 23502, United States

Conditions

Explore the condition pages connected to this study.

SMALL CELL LUNG CANCER