New combo therapy tested in fight against advanced lung cancer

NCT ID NCT05014815

Completed Disease control Sponsor: BeiGene Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding a new drug called ociperlimab to an existing immunotherapy (tislelizumab) and standard chemotherapy was more effective and safe for people with advanced non-small cell lung cancer that had not been treated before. It involved 272 participants whose cancer was either locally advanced, could not be surgically removed, or had spread. The main goal was to see if the three-drug combination could better control the cancer and delay its progression compared to the two-drug regimen.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Ajou University Hospital

Suwon, 16499, South Korea
Ansteel Group General Hospital

Anshan, Liaoning, 114000, China
Beijing Cancer Hospital

Beijing, Beijing Municipality, 100142, China
Border Medical Oncology

East Albury, New South Wales, 2640, Australia
Cancer Care Northwest

Spokane Valley, Washington, 99216-1020, United States
Cancer Center of Guangzhou Medical University

Guangzhou, Guangdong, 510030, China
Centre Hospitalier Regional Universitaire de Caen

Caen, 14000, France
Centro Oncologico de Galicia

A Coruña, 15009, Spain
Ch Provincial de Castellon

Castellon, 50009, Spain
Cha Bundang Medical Center, Cha University

BundangGu SeongnamSi, Gyeonggi-do, 13496, South Korea
Changzhou Cancer Hospital

Changzhou, Jiangsu, 213001, China
Complejo Asistencial Universitario de Leon

León, 24071, Spain
Comprehensive Cancer Center of Nevada

Las Vegas, Nevada, 89169-3321, United States
Daping Hospital, Third Military Medical University

Chongqing, Chongqing Municipality, 400042, China
Dong A University Hospital

Seogu, Busan Gwang'yeogsi, 49201, South Korea
Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, 200000, China
Fujian Cancer Hospital

Fuzhou, Fujian, 350014, China
Fundacion Instituto Valenciano de Oncologia Ivo

Valencia, 46009, Spain
Gangnam Severance Hospital, Yonsei University Health System

Seoul, Seoul Teugbyeolsi, 06273, South Korea
Harbin Medical University Cancer Hospital

Harbin, Heilongjiang, 150000, China
Hopital Charles Nicolle Clinique Pneumologique

Rouen, 76000, France
Hopital Europeen Georges Pompidou

Paris, 75015, France
Hospital Universitario Central de Asturias

Oviedo, 33011, Spain
Huashan Hospital Affiliated to Fudan University

Shanghai, Shanghai Municipality, 200040, China
Huzhou Central Hospital

Huzhou, Zhejiang, 313003, China
Institut Curie

Paris, 75005, France
Jingzhou Central Hospital

Jingzhou, Hubei, 434020, China
Jinhua Municipal Central Hospital

Jinhua, Zhejiang, 321000, China
Kangbuk Samsung Hospital

JongnoGu, Seoul Teugbyeolsi, 03181, South Korea
Klinik Penzing Wien, Abteilung Fur Atemwegs

Vienna, 1140, Austria
Korea University Guro Hospital

GuroGu, Seoul Teugbyeolsi, 08308, South Korea
Launceston General Hospital

Launceston, Tasmania, 7250, Australia
Liaocheng Peoples Hospital

Liaocheng, Shandong, 252000, China
North Shore Hematology Oncology Associates Dba New York Cancer and Blood Specialists

Port Jefferson Station, New York, 11776-8066, United States
North Shore Hematology Oncology Associates Dba New York Cancer and Blood Specialists (New York)

New York, New York, 10028-0517, United States
Northern Beaches Hospital

Frenchs Forest, New South Wales, 2086, Australia
Ny Cancer and Blood Specialists

The Bronx, New York, 10469-5930, United States
Olivia Newton John Cancer Wellness and Research Centre

Heidelberg, Victoria, 3084, Australia
Peninsula and South Eastern Haematology and Oncology Group

Frankston, Victoria, 3199, Australia
Port Macquarie Base Hospital

Port Macquarie, New South Wales, 2444, Australia
Rj Zuckerberg Cancer Center

New Hyde Park, New York, 11042-1118, United States
Samsung Medical Center

GangnamGu, Seoul Teugbyeolsi, 06351, South Korea
Seoul National University Hospital

Seoul, Seoul Teugbyeolsi, 03080, South Korea
Severance Hospital Yonsei University Health System

SeodaemunGu, Seoul Teugbyeolsi, 03722, South Korea
Shandong Cancer Hospital

Jinan, Shandong, 250117, China
Shanghai Pulmonary Hospital

Shanghai, Shanghai Municipality, 200433, China
St Lukes Hospital

Thessaloniki, 55236, Greece
Tennessee Cancer Specialist

Knoxville, Tennessee, 37909-1327, United States
Texas Oncology Tyler Longview

Austin, Texas, 78705-1163, United States
The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, 450052, China
The First Hospital of Jiaxing

Jiaxing, Zhejiang, 314001, China
The First Hospital of Lanzhou University

Lanzhou, Gansu, 730000, China
The First Peoples Hospital of Chenzhou

Chenzhou, Hunan, 423000, China
The First Peoples Hospital of Kashgar

Kashgar, Xinjiang, 844099, China
Toowoomba Hospital

Toowoomba, Queensland, 4350, Australia
Townsville University Hospital

Douglas, Queensland, 4814, Australia
Ulsan University Hospital

Donggu, Ulsan Gwang'yeogsi, 44033, South Korea
University of Iowa Hospitals and Clinics

Iowa City, Iowa, 52242-1009, United States
Valkyrie Clinical Trials

Los Angeles, California, 90067-2011, United States
West China Hospital, Sichuan University

Chengdu, Sichuan, 610041, China
Xcancerdayton Physician Network

Dayton, Ohio, 45409-1328, United States
Xinqiao Hospital Affiliated to the Army Medical University

Chongqing, Chongqing Municipality, 400037, China
Zhejiang Cancer Hospital

Hangzhou, Zhejiang, 310022, China
Zhejiang Provincial Peoples Hospital

Hangzhou, Zhejiang, 310014, China

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED, UNRESECTABLE, OR METASTATIC NONSMALL CELL LUNG CANCER (NSCLC) NONSMALL CELL LUNG CANCER, STAGE IIIB NONSMALL CELL LUNG CANCER, STAGE IV