New drug duo aims to fight tough lung cancers

NCT ID NCT05908734

Summary

This study is testing the safety and effectiveness of combining two drugs, amivantamab and cetrelimab, for people with advanced non-small cell lung cancer that has spread. The first part finds the best dose, and the second part checks how well that dose shrinks tumors in specific groups of patients. It involves 71 people whose cancer has progressed after standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ASST Grande Ospedale Metropolitano Niguarda

    Milan, 20162, Italy

  • Adana City Hospital

    Adana, 01170, Turkey (Türkiye)

  • Ankara Bilkent Sehir Hastanesi

    Ankara, 06800, Turkey (Türkiye)

  • Aou San Luigi Gonzaga

    Orbassano, 10043, Italy

  • Bakirkoy Sadi Konuk Training and Research Hospital

    Istanbul, 34147, Turkey (Türkiye)

  • CIONC Centro Integrado de Oncologia de Curitiba

    Curitiba, 80810 050, Brazil

  • Cancer and Blood Specialty Clinic

    Los Alamitos, California, 90720, United States

  • Centro Ricerche Cliniche di Verona S r l

    Verona, 37134, Italy

  • Cetus Oncologia

    Belo Horizonte, 30110 022, Brazil

  • City of Hope

    Duarte, California, 91010, United States

  • City of Hope Orange County Lennar Foundation Cancer Center

    Irvine, California, 92618, United States

  • Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi

    Ankara, 06200, Turkey (Türkiye)

  • European Institute of Oncology

    Milan, 20141, Italy

  • Freeman Hospital

    Newcastle, NE7 7DN, United Kingdom

  • Fundacao Antonio Prudente A C Camargo Cancer Center

    São Paulo, 01509 900, Brazil

  • Fundacao Pio XII

    Barretos, 14784 400, Brazil

  • Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi

    Istanbul, 34722, Turkey (Türkiye)

  • Hosp Univ Vall D Hebron

    Barcelona, 08035, Spain

  • Hosp. Gral. Univ. de Alicante

    Alicante, 03010, Spain

  • Hosp. Univ. 12 de Octubre

    Madrid, 28041, Spain

  • Hosp. Univ. Quiron Dexeus

    Barcelona, 8028, Spain

  • Hosp. Virgen Macarena

    Seville, 41009, Spain

  • Hospital Nossa Senhora da Conceicao S A

    Porto Alegre, 91350 200, Brazil

  • Hospital Santa Izabel Santa Casa de Misericordia da Bahia

    Salvador, 40050-410, Brazil

  • Hospital Umum Sarawak

    Kuching, 93586, Malaysia

  • Hospital do Cancer de Londrina

    Londrina, 86015 520, Brazil

  • INSTYTUT GENETYKI I IMMUNOLOGII GENIM Sp z o o

    Lublin, 20 609, Poland

  • Imperial College London and Imperial College Healthcare NHS Trust

    London, W6 8RF, United Kingdom

  • Instituto Valenciano de Oncologia

    Valencia, 46009, Spain

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Medicana International Izmir

    Izmir, 35170, Turkey (Türkiye)

  • Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy

    Warsaw, 02 781, Poland

  • PERSONAL Oncologia de Precisao e Personalizada

    Belo Horizonte, 30130 090, Brazil

  • Providence Oncology and Hematology Care Clinic Westside

    Portland, Oregon, 97225, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Royal Marsden Hospital

    Sutton, SM2 5PT, United Kingdom

  • Sakarya Universitesi Egitim Ve Arastırma Hastanesi

    Sakarya, 54100, Turkey (Türkiye)

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • University Malaya Medical Centre

    Kuala Lumpur, 59100, Malaysia

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

  • Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeylandow

    Poznan, 60 569, Poland

Conditions

Explore the condition pages connected to this study.