New drug duo targets tough lung cancers
NCT ID NCT05488314
Summary
This study is testing a combination of two drugs, amivantamab and capmatinib, for people with advanced non-small cell lung cancer that has spread and cannot be removed by surgery. The first part aims to find a safe and effective dose. The second part will see how well this dose works to shrink tumors in people whose cancer has specific genetic changes called MET mutations.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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ASST Grande Ospedale Metropolitano Niguarda
Milan, 20162, Italy
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Ankara Bilkent City Hospital
Ankara, 06800, Turkey (Türkiye)
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Ankara Bilkent Sehir Hastanesi
Çankaya, 06800, Turkey (Türkiye)
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Asan Medical Center
Seoul, 05505, South Korea
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Beijing Cancer Hospital
Beijing, 100142, China
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CHU de la Timone
Marseille, 13005, France
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CIONC Centro Integrado de Oncologia de Curitiba
Curitiba, 80810 050, Brazil
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Charite Universitaetsmedizin Berlin
Berlin, 12203, Germany
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Chongqing University Cancer Hospital
Chongqing, 400030, China
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Chonnam National University Hwasun Hospital
Jeollanam-do, 58128, South Korea
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Chungbuk National University Hospital
Cheongju-si, 28644, South Korea
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Fondazione G Pascale Istituto Nazionale Tumori IRCCS
Naples, 80131, Italy
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Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, 20133, Italy
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Fudan University Shanghai Cancer Center
Shanghai, 200032, China
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Fundacao Antonio Prudente A C Camargo Cancer Center
São Paulo, 01509 900, Brazil
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Gachon University Gil Medical Center
Incheon, 21565, South Korea
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Gazi University Hospital
Ankara, 06560, Turkey (Türkiye)
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Henan Cancer Hospital
Zhengzhou, 450008, China
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Hosp Clinic de Barcelona
Barcelona, 08036, Spain
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Hosp Univ A Coruna
A Coruña, 15006, Spain
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Hosp Univ Fund Jimenez Diaz
Madrid, 28040, Spain
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Hosp Univ Vall D Hebron
Barcelona, 08035, Spain
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Hosp. Clinico Univ. de Valencia
Valencia, 46010, Spain
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Hosp. Del Mar
Barcelona, 08003, Spain
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Hosp. Gral. Univ. de Alicante
Alicante, 03010, Spain
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Hosp. Univ. 12 de Octubre
Madrid, 28041, Spain
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Hosp. Univ. La Paz
Madrid, 28046, Spain
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Hosp. Univ. Quiron Dexeus
Barcelona, 08028, Spain
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Hosp. Virgen Macarena
Seville, 41009, Spain
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Huizhou Municipal Central Hospital
Huizhou, 516001, China
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INSTYTUT GENETYKI I IMMUNOLOGII GENIM Sp z o o
Lublin, 20 609, Poland
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Imperial College London and Imperial College Healthcare NHS Trust
London, W2 1NY, United Kingdom
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Institut de cancerologie de l'ouest
Saint-Herblain, 44805, France
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Institute Coeur Poumon
Lille, 59000, France
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Instituto D Or de Pesquisa e Ensino IDOR
Rio de Janeiro, 22281 100, Brazil
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Istituto Nazionale Tumori Regina Elena
Rome, 00128, Italy
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Istituto Oncologico Veneto - IRCCS
Padua, 35128, Italy
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Klinikum Chemnitz gGmbH
Chemnitz, 09116, Germany
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Montefiore Einstein Center for Cancer Care
The Bronx, New York, 10467, United States
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Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy
Warsaw, 02 781, Poland
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National Cancer Center
Goyang-si, 10408, South Korea
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National Hospital Organization Nagoya Medical Center
Nagoya, 460-0001, Japan
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Nouvel Hopital Civil - CHU Strasbourg
Strasbourg, 67091, France
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Nucleo de Oncologia da Bahia
Salvador, 40170 110, Brazil
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Oncoclinicas Rio de Janeiro S A
Rio de Janeiro, 22 250 905, Brazil
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Ospedale S. Maria Delle Croci
Ravenna, 48121, Italy
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PERSONAL Oncologia de Precisao e Personalizada
Belo Horizonte, 30130-090, Brazil
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Princess Margaret Cancer Centre University Health Network
Toronto, Ontario, M5G 1Z5, Canada
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Royal Marsden Hospital
Sutton, SM2 5PT, United Kingdom
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Second Affiliated Hospital, School of Medicine, Zhejiang University
Hangzhou, 310009, China
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Seoul National University Bundang Hospital
Seongnam, 13620, South Korea
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Seoul National University Hospital
Seoul, 03080, South Korea
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Severance Hospital Yonsei University Health System
Seoul, 03722, South Korea
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Shanghai Pulmonary Hospital
Shanghai, 200433, China
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Shengjing Hospital Of China Medical University
Shenyang, 110055, China
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Shizuoka Cancer Center
Sunto Gun, 411 8777, Japan
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Sichuan Cancer Hospital
Chengdu, 610041, China
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Sir Bobby Robson Cancer Trials Research Centre
Newcastle upon Tyne, NE7 7DN, United Kingdom
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Sir Run Run Shaw Hospital Zhejiang University School of Medicine
Hangzhou, 310016, China
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Sociedade Beneficente de Senhoras Hospital Sirio Libanes
São Paulo, 01308 901, Brazil
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The Cancer Institute Hospital of JFCR
Tokyo, 135 8550, Japan
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The First Affiliated Hospital Sun Yat sen University
Guangzhou, 510060, China
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The First Affiliated Hospital of Xian Jiaotong University
Xi'an, 710061, China
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The Oncology Institute of Hope and Innovation
Cerritos, California, 90703, United States
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The Ottawa Hospital Research Institute
Ottawa, Ontario, K1Y 4E9, Canada
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UCLA
Los Angeles, California, 90095, United States
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UPCO Unidade de Pesquisa Clinica em Oncologia
Pelotas, 96020 080, Brazil
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Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da PUCRS
Porto Alegre, 90610-000, Brazil
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Universitaetsklinikum Carl Gustav Carus TU Dresden
Dresden, 01307, Germany
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Universitaetsklinikum Essen
Essen, 45147, Germany
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Universitaetsklinikum Koeln
Cologne, 50937, Germany
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Universitaetsklinikum Muenster
Münster, 48149, Germany
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University College London Hospitals Nhs Foundation Trust
London, NW1 2PG, United Kingdom
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University of Alabama at Birmingham, Comprehensive Cancer Center
Birmingham, Alabama, 35233, United States
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Uniwersyteckie Centrum Kliniczne
Gdansk, 80 214, Poland
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Virginia Cancer Specialists
Fairfax, Virginia, 22031, United States
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West China Hospital Sichuan University
Chengdu, 610041, China
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Yantai Yuhuangding Hospital
Yantai, 264000, China
Conditions
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