New drug duo targets tough lung cancers

NCT ID NCT05488314

Summary

This study is testing a combination of two drugs, amivantamab and capmatinib, for people with advanced non-small cell lung cancer that has spread and cannot be removed by surgery. The first part aims to find a safe and effective dose. The second part will see how well this dose works to shrink tumors in people whose cancer has specific genetic changes called MET mutations.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARCINOMA, NON-SMALL-CELL LUNG are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • ASST Grande Ospedale Metropolitano Niguarda

    Milan, 20162, Italy

  • Ankara Bilkent City Hospital

    Ankara, 06800, Turkey (Türkiye)

  • Ankara Bilkent Sehir Hastanesi

    Çankaya, 06800, Turkey (Türkiye)

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Beijing Cancer Hospital

    Beijing, 100142, China

  • CHU de la Timone

    Marseille, 13005, France

  • CIONC Centro Integrado de Oncologia de Curitiba

    Curitiba, 80810 050, Brazil

  • Charite Universitaetsmedizin Berlin

    Berlin, 12203, Germany

  • Chongqing University Cancer Hospital

    Chongqing, 400030, China

  • Chonnam National University Hwasun Hospital

    Jeollanam-do, 58128, South Korea

  • Chungbuk National University Hospital

    Cheongju-si, 28644, South Korea

  • Fondazione G Pascale Istituto Nazionale Tumori IRCCS

    Naples, 80131, Italy

  • Fondazione IRCCS Istituto Nazionale dei Tumori

    Milan, 20133, Italy

  • Fudan University Shanghai Cancer Center

    Shanghai, 200032, China

  • Fundacao Antonio Prudente A C Camargo Cancer Center

    São Paulo, 01509 900, Brazil

  • Gachon University Gil Medical Center

    Incheon, 21565, South Korea

  • Gazi University Hospital

    Ankara, 06560, Turkey (Türkiye)

  • Henan Cancer Hospital

    Zhengzhou, 450008, China

  • Hosp Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hosp Univ A Coruna

    A Coruña, 15006, Spain

  • Hosp Univ Fund Jimenez Diaz

    Madrid, 28040, Spain

  • Hosp Univ Vall D Hebron

    Barcelona, 08035, Spain

  • Hosp. Clinico Univ. de Valencia

    Valencia, 46010, Spain

  • Hosp. Del Mar

    Barcelona, 08003, Spain

  • Hosp. Gral. Univ. de Alicante

    Alicante, 03010, Spain

  • Hosp. Univ. 12 de Octubre

    Madrid, 28041, Spain

  • Hosp. Univ. La Paz

    Madrid, 28046, Spain

  • Hosp. Univ. Quiron Dexeus

    Barcelona, 08028, Spain

  • Hosp. Virgen Macarena

    Seville, 41009, Spain

  • Huizhou Municipal Central Hospital

    Huizhou, 516001, China

  • INSTYTUT GENETYKI I IMMUNOLOGII GENIM Sp z o o

    Lublin, 20 609, Poland

  • Imperial College London and Imperial College Healthcare NHS Trust

    London, W2 1NY, United Kingdom

  • Institut de cancerologie de l'ouest

    Saint-Herblain, 44805, France

  • Institute Coeur Poumon

    Lille, 59000, France

  • Instituto D Or de Pesquisa e Ensino IDOR

    Rio de Janeiro, 22281 100, Brazil

  • Istituto Nazionale Tumori Regina Elena

    Rome, 00128, Italy

  • Istituto Oncologico Veneto - IRCCS

    Padua, 35128, Italy

  • Klinikum Chemnitz gGmbH

    Chemnitz, 09116, Germany

  • Montefiore Einstein Center for Cancer Care

    The Bronx, New York, 10467, United States

  • Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy

    Warsaw, 02 781, Poland

  • National Cancer Center

    Goyang-si, 10408, South Korea

  • National Hospital Organization Nagoya Medical Center

    Nagoya, 460-0001, Japan

  • Nouvel Hopital Civil - CHU Strasbourg

    Strasbourg, 67091, France

  • Nucleo de Oncologia da Bahia

    Salvador, 40170 110, Brazil

  • Oncoclinicas Rio de Janeiro S A

    Rio de Janeiro, 22 250 905, Brazil

  • Ospedale S. Maria Delle Croci

    Ravenna, 48121, Italy

  • PERSONAL Oncologia de Precisao e Personalizada

    Belo Horizonte, 30130-090, Brazil

  • Princess Margaret Cancer Centre University Health Network

    Toronto, Ontario, M5G 1Z5, Canada

  • Royal Marsden Hospital

    Sutton, SM2 5PT, United Kingdom

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    Hangzhou, 310009, China

  • Seoul National University Bundang Hospital

    Seongnam, 13620, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • Shanghai Pulmonary Hospital

    Shanghai, 200433, China

  • Shengjing Hospital Of China Medical University

    Shenyang, 110055, China

  • Shizuoka Cancer Center

    Sunto Gun, 411 8777, Japan

  • Sichuan Cancer Hospital

    Chengdu, 610041, China

  • Sir Bobby Robson Cancer Trials Research Centre

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Sir Run Run Shaw Hospital Zhejiang University School of Medicine

    Hangzhou, 310016, China

  • Sociedade Beneficente de Senhoras Hospital Sirio Libanes

    São Paulo, 01308 901, Brazil

  • The Cancer Institute Hospital of JFCR

    Tokyo, 135 8550, Japan

  • The First Affiliated Hospital Sun Yat sen University

    Guangzhou, 510060, China

  • The First Affiliated Hospital of Xian Jiaotong University

    Xi'an, 710061, China

  • The Oncology Institute of Hope and Innovation

    Cerritos, California, 90703, United States

  • The Ottawa Hospital Research Institute

    Ottawa, Ontario, K1Y 4E9, Canada

  • UCLA

    Los Angeles, California, 90095, United States

  • UPCO Unidade de Pesquisa Clinica em Oncologia

    Pelotas, 96020 080, Brazil

  • Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da PUCRS

    Porto Alegre, 90610-000, Brazil

  • Universitaetsklinikum Carl Gustav Carus TU Dresden

    Dresden, 01307, Germany

  • Universitaetsklinikum Essen

    Essen, 45147, Germany

  • Universitaetsklinikum Koeln

    Cologne, 50937, Germany

  • Universitaetsklinikum Muenster

    Münster, 48149, Germany

  • University College London Hospitals Nhs Foundation Trust

    London, NW1 2PG, United Kingdom

  • University of Alabama at Birmingham, Comprehensive Cancer Center

    Birmingham, Alabama, 35233, United States

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, 80 214, Poland

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

  • West China Hospital Sichuan University

    Chengdu, 610041, China

  • Yantai Yuhuangding Hospital

    Yantai, 264000, China

Conditions

Explore the condition pages connected to this study.