New hope for lung cancer patients when standard drugs fail

NCT ID NCT04001777

Summary

This early-stage study is testing whether adding an experimental drug called APG-1252 to an existing lung cancer medication (osimertinib) is safe and might help control tumors that have started growing again. The trial will enroll about 80 adults with advanced non-small cell lung cancer that has an EGFR mutation and has progressed despite previous treatments. Researchers will first find the safest dose of the combination, then see if it can shrink tumors in patients whose cancer has become resistant to current therapies.

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Contacts and locations

Locations

  • First Hospital of Jilin University

    Changchun, Jilin, China

  • Henan Provincial people's Hospital

    Zhengzhou, Henan, China

  • Jilin Provincial Cancer Hospital

    Changchun, Jilin, China

  • Sun-Yat Sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

Conditions

Explore the condition pages connected to this study.