New cancer drug LUNA18 tested in early trial – but study halted

NCT ID NCT05012618

First seen Jan 07, 2026 · Last updated May 13, 2026 · Updated 19 times

Summary

This early-phase study tested a new drug called LUNA18, alone or with other cancer drugs, in 128 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the right dose, and see if the drug could shrink tumors. The study was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Abramson Cancer Center at Pennsylvania Hospital

    Philadelphia, Pennsylvania, 19106, United States

  • Aichi Cancer Center

    Nagoya, Aichi-ken, 464-8681, Japan

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Beth Israel Deaconess

    Boston, Massachusetts, 02215, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • NEXT Oncology

    Austin, Texas, 78758, United States

  • NEXT Virginia

    Fairfax, Virginia, 22031, United States

  • National Cancer Center Hospital

    Chuo-Ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

  • National Hospital Organization Kyushu Cancer Center

    Fukuoka, 811-1395, Japan

  • Osaka International Cancer Institute

    Osaka, 541-8567, Japan

  • Renown Regional Medical Center

    Reno, Nevada, 89502, United States

  • Rhode Island Hospital-Comprehensive Cancer Center

    Providence, Rhode Island, 02903, United States

  • Shizuoka Cancer Center

    Nakatogari, Shizuoka, 411-0934, Japan

  • South Texas Accelerated Research Therapeutics (START) Midwest

    Grand Rapids, Michigan, 49546, United States

  • The Cancer Institute Hospital of JFCR

    Koto-ku, Tokyo, 135-8550, Japan

  • University of California - Davis

    Davis, California, 95616, United States

  • University of Wisconsin - Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

Conditions

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