New inhaled drug aims to fight deadly lung scarring
NCT ID NCT06968845
First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 4 times
Summary
This Phase 2 trial tests an experimental inhaled medication called LTI-03 in about 120 people with idiopathic pulmonary fibrosis (IPF), a progressive lung disease that causes scarring and breathing difficulty. Participants will inhale LTI-03 or a placebo twice daily for 24 weeks. The study measures safety, lung function, and changes in lung scarring via scans and questionnaires.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LTI-03 (an experimental inhaled peptide)
What this could lead to
If successful, LTI-03 could offer a new treatment option that protects lung cells and reduces scarring, potentially slowing disease progression in IPF patients.
What could go wrong
This is an early Phase 2 trial with only 120 participants, so results may not confirm benefit. The drug is compared to placebo, and side effects or lack of efficacy are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Locations
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Cedars Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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Cleveland Clinic Florida
RECRUITINGWeston, Florida, 33331, United States
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El Paso Pulmonary Association
RECRUITINGEl Paso, Texas, 79902, United States
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Henry Ford Health
RECRUITINGDetroit, Michigan, 48202, United States
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Launceston Respiratory and Sleep Centre
RECRUITINGLaunceston, Tasmania, 7250, Australia
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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National Jewish Health
RECRUITINGDenver, Colorado, 80206, United States
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Paradigm Clinical Research Centers, LLC
RECRUITINGSan Diego, California, 92108, United States
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Royal Brompton Hospital
RECRUITINGLondon, SW3 6HP, United Kingdom
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Royal Devon and Exeter Hospital
RECRUITINGExeter, Devon, EX2 5DW, United Kingdom
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Royal Infirmary of Edinburgh
RECRUITINGEdinburgh, Scotland, EH16 4SA, United Kingdom
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Royal Papworth Hospital
RECRUITINGTrumpington, Cambridge, CB2 0AY, United Kingdom
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Salus Aegroti Praktyka Lekarska dr n. med. Grzegorz Gąsior
RECRUITINGSosnowiec, Silesian Voivodeship, 41-208, Poland
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The Lung Research Center, LLC
RECRUITINGChesterfield, Missouri, 63017, United States
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UAB Lung Health Center
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Kansas Medical Center
RECRUITINGKansas City, Missouri, 66160, United States
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27514, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84108, United States
Contact Email: •••••@•••••
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Westmead Hospital
RECRUITINGWestmead, New South Wales, 2145, Australia
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Yale University School of Medicine
RECRUITINGNew Haven, Connecticut, 06511, United States
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