New hope for controlling devastating seizures in severe childhood epilepsies

NCT ID NCT06908226

Summary

This study is testing the long-term safety and effectiveness of an investigational drug called LP352 for reducing seizures in children and adults with severe developmental and epileptic encephalopathies (DEEs), such as Dravet and Lennox-Gastaut syndromes. It is open to about 324 people who have already completed earlier LP352 studies. The main goal is to see how well the drug controls seizures over time and to monitor for any side effects during approximately 14 months of treatment.

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Contacts and locations

Locations

  • AP-HP - Hôpital universitaire Robert-Debré

    Paris, 75019, France

  • Arkansas Children's Hospital - PIN

    Little Rock, Arkansas, 72202-3500, United States

  • Austin Hospital

    Heidelberg, Victoria, 3084, Australia

  • Children's Clinical University Hospital

    Riga, LV-1004, Latvia

  • David Geffen School of Medicine at UCLA

    Los Angeles, California, 90095, United States

  • Hospital Ruber Internacional (Grupo Quironsalud)

    Madrid, 28034, Spain

  • Hospital Universitario Vithas Madrid La Milagrosa

    Madrid, 28010, Spain

  • Hospital de La Santa Creu i Sant Pau

    Barcelona, 8041, Spain

  • Institute of Neurology and Neurosurgery at Saint Barnabas, LLC

    Livingston, New Jersey, 07039-5817, United States

  • Mid-Atlantic Epilepsy and Sleep Center

    Bethesda, Maryland, 20817-1809, United States

  • Mother and Child Health Care Institute of Serbia Dr Vukan Cupic

    Belgrade, 11000, Serbia

  • NW FL Clinical Research Group, LLC

    Gulf Breeze, Florida, 32561-4458, United States

  • Northeast Regional Epilepsy Group - Morristown - 310 Madison Ave

    Morristown, New Jersey, 07960, United States

  • Pediatric Epilepsy and Neurology Specialists

    Tampa, Florida, 33609-4181, United States

  • Research Institute of Orlando LLC

    Orlando, Florida, 32806-5411, United States

  • The University of Texas Medical School at Houston

    Houston, Texas, 77030-3000, United States

Conditions

Explore the condition pages connected to this study.