New hope for controlling devastating childhood epilepsies

NCT ID NCT05626634

Summary

This study tested the long-term safety of an add-on epilepsy drug called LP352 for people with severe, hard-to-treat epilepsies like Dravet and Lennox-Gastaut syndromes. It followed 41 participants for up to a year to see if the drug was safe to take continuously and if it helped reduce their seizures. The main goal was to check for side effects, while also measuring changes in seizure frequency and mood.

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Contacts and locations

Locations

  • Advent Health Orlando

    Orlando, Florida, 32803, United States

  • Alfred Health

    Melbourne, Victoria, 3004, Australia

  • Arkansas Children's Hospital

    Little Rock, Arkansas, 72202, United States

  • Austin Epilepsy Care Center

    Austin, Texas, 78758, United States

  • Austin Health

    Heidelberg, Victoria, 3084, Australia

  • Boston Children's Health Physicians LLP

    Hawthorne, New York, 10532, United States

  • Child Neurology Consultants of Austin

    Austin, Texas, 78757, United States

  • Hawaii Pacific Neuroscience

    Honolulu, Hawaii, 96817, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mid-Atlantic Epilepsy and Sleep Center

    Bethesda, Maryland, 20817, United States

  • Northeast Regional Epilepsy Group

    Staten Island, New York, 10305, United States

  • Northwell Health

    New York, New York, 10075, United States

  • Northwest Florida Clinical Research Group

    Gulf Breeze, Florida, 32561, United States

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, 60611, United States

  • OnSite Clinical Solutions LLC

    Charlotte, North Carolina, 98277, United States

  • Providence Neurological Specialties-East

    Portland, Oregon, 97213, United States

  • Queensland Children's Hospital

    South Brisbane, Queensland, 4101, Australia

  • Rancho Los Amigos National Rehabilitation Center (RLANRC)

    Downey, California, 90242, United States

  • Research Institute of Orlando

    Orlando, Florida, 32806, United States

  • Spectrum Health

    Grand Rapids, Michigan, 49503, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California San Francisco

    San Francisco, California, 94158, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of South Florida

    Tampa, Florida, 33606, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • University of Washington Valley Medical Center

    Renton, Washington, 98055, United States

  • Wake Forest University School of Medicine

    Winston-Salem, North Carolina, 27157, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.