New allergy shot shows promise for those failed by standard meds

NCT ID NCT06046391

First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 22 times

Summary

This study tested a new drug called LP-003 in 180 adults with moderate to severe seasonal allergies that were not well controlled by standard treatments like antihistamines or nasal sprays. LP-003 is a lab-made antibody that blocks IgE, a key driver of allergic reactions, and is designed to work better and last longer than existing options. Participants received either the drug or a placebo for 12 weeks, and researchers tracked their daily nasal symptoms to see if LP-003 could provide better relief.

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Contacts and locations

Locations

  • Beijing Shijitan Hospital

    Beijing, Beijing Municipality, 100038, China

  • Changchun University of Chinese Medicine Affiliated Hospital

    Changchun, Jilin, China

  • Dongfang Hospital

    Beijing, Beijing Municipality, China

  • Linfen Peoples Hospital

    Linfen, Shanxi, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, China

  • Peking University Third Hospital

    Beijing, Beijing Municipality, China

  • Second hospital of Shanxi Medical University University

    Taiyuan, Shanxi, China

  • Shengjing Hospital of China Medical University

    Shenyang, Liaoning, China

  • The First Hospital of Shanxi Medical University

    Taiyuan, Shanxi, China

  • Tianjin Peoples Hospital

    Tianjing, Tianjing, China

  • Tonghua central hospital

    Tonghua, Jilin, China

  • Xidian group hospital

    Xi’an, Shanxi, China

  • Yan Bian Chao Yi Hospital

    Yanbian, Jilin, China

  • Yanbian University hospital

    Yanji, Jilin, China

  • Yinchuan Peoples Hospital

    Yinchuan, Ningxia, China

  • Zhengzhou central hospital

    Zhengzhou, Henan, China

  • Zibo central hospital

    Zibo, Shandong, China

Conditions

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