Heart surgery study questions standard drug dose to reduce risks
NCT ID NCT07477977
Summary
This study aims to find the safest and most effective dose of a drug called protamine, which is used to reverse blood thinners after heart surgery using a heart-lung machine. Researchers will compare three different dosing strategies in 195 adults having planned heart surgery. The goal is to see if using less protamine can still control bleeding while causing fewer side effects like low blood pressure or allergic reactions.
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