Could less radiation be better for some head and neck cancers?
NCT ID NCT07328854
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a lower dose of radiation (40.2Gy) to the standard dose (49.2Gy) for people with stage II nasopharyngeal cancer that responds well to chemotherapy. All participants also receive immunotherapy. The goal is to see if the lower dose can control the cancer just as well while causing fewer side effects. About 346 adults aged 18 to 75 are being recruited.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Anhui Provincial Cancer Hospital
RECRUITINGHefei, Anhui, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cancer Hospital of Shantou University Medical College
RECRUITINGShantou, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Central South University Cancer Hospital,
RECRUITINGChangsha, Hunan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fujian Cancer Hospital
RECRUITINGFuzhou, Fujian, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Guangxi Medical University Cancer Hospital
RECRUITINGNanning, Guangxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sun Yat-sen University cancer center
RECRUITINGGuangzhou, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Fifth Affiliated Hospital of Sun Yat-sen University
RECRUITINGZhuhai, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Kunming Medical University
RECRUITINGKunming, Yunnan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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West China Hospital, Sichuan University
RECRUITINGChengdu, Sichuan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wuzhou Red Cross Hospital
RECRUITINGWuzhou, Guangxi, China
Contact Phone: •••-•••-••••
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Xiangya Hospital of Central South University
RECRUITINGChangsha, Hunan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yunnan Cancer Hospital
RECRUITINGKunming, Yunnan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhejiang Cancer Hospital
RECRUITINGHangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhongshan City People's Hospital
RECRUITINGZhongshan, Guangdong, China
Contact Phone: •••-•••-••••
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the Affiliated Cancer Hospital of Guangzhou Medical University
RECRUITINGGuangzhou, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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- Immunotherapy combo shows promise in shrinking Hard-to-Treat head and neck tumors
- Immunotherapy duo aims to shrink nasopharyngeal tumors before standard treatment
- New radiation approach aims to reduce dry mouth in throat cancer patients
- New pill-chemo combo takes on hard-to-treat cancers
- Immune boosting duo takes on rare throat cancer