Could a lower dose of a transplant drug be better for blood cancer patients?
NCT ID NCT05436418
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 26 times
Summary
This study tests whether a lower dose of the drug cyclophosphamide, given after a stem cell transplant, can better prevent graft-versus-host disease (a common complication where donor cells attack the patient's body) in people with blood cancers like leukemia or lymphoma. About 260 adults who need a transplant from a related donor will receive different doses of the drug along with other medications. Researchers will monitor participants for up to 5 years to find the safest and most effective dose.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope
NOT_YET_RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-••••
Conditions
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