Could a lower drug dose make bone marrow transplants safer for older patients?
NCT ID NCT04959175
First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 26 times
Summary
This study aims to see if a lower dose of the drug cyclophosphamide can prevent graft-versus-host disease (a common complication where donor cells attack the body) while causing fewer side effects in older or frail adults with blood cancers. Participants will receive a bone marrow transplant and then the lower-dose drug. The goal is to improve transplant success and quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital of the University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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