New hope for nighttime cluster headaches: sleep drug shows promise in trial
NCT ID NCT06950281
First seen Jan 04, 2026 · Last updated Jun 16, 2026 · Updated 31 times
Summary
This study tests whether a low-sodium version of the sleep drug oxybate (Xywav) can safely reduce the number of nighttime cluster headache attacks in people with chronic cluster headache. About 52 adults will take either the drug or a placebo twice nightly for 16 weeks. The main goal is to see if the drug lowers the weekly count of attacks that occur between 10 PM and 7 AM.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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