New hope for night-time cluster headache sufferers: sleep drug xywav tested in trial

NCT ID NCT06950281

First seen Jan 04, 2026 · Last updated May 01, 2026 · Updated 21 times

Summary

This study tests whether a low-sodium form of oxybate (Xywav) can reduce the number of nighttime cluster headache attacks in people with chronic cluster headache. About 52 adults will take either the drug or a placebo twice nightly for 16 weeks. The main goal is to see if the drug lowers the weekly count of headaches that wake people from sleep.

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