Can sound waves soothe pain? new study probes Brain's response

NCT ID NCT06343883

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times

Summary

This study is testing how different pressure levels of low-intensity focused ultrasound (LIFU) affect brain activity related to pain. Researchers will use EEG and fMRI to measure brain responses in 25 healthy adults before and after ultrasound. The goal is to understand how LIFU might influence pain processing, not to treat pain directly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
low-intensity focused ultrasound (device)
What this could lead to
If successful, this could help researchers understand how ultrasound might be used to manage pain in the future.
What could go wrong
This is a very early, small study (25 people) focused on measuring brain activity, not treating pain. It may not lead to any direct treatment.

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Conditions

The condition(s) this trial relates to.

Nociceptive Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fralin Biomedical Research Institute at VTC

    Roanoke, Virginia, 24016, United States

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Other studies related to the condition(s) this trial covers.