Less painkiller, better breathing? a nerve block trial puts it to the test
NCT ID NCT07792044
First seen Aug 28, 2026 · Last updated Aug 28, 2026
Summary
This trial tests whether a low dose of liposomal bupivacaine, a long-acting local anesthetic, can provide pain relief equal to the standard dose after arthroscopic shoulder surgery. The study enrolls adults having shoulder procedures like rotator cuff repair. Researchers will compare pain scores at rest and during movement, as well as breathing function and side effects. The goal is to see if a smaller dose can reduce diaphragm weakness and other complications while still keeping patients comfortable.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- liposomal bupivacaine (a long-acting local anesthetic) given as a nerve block before shoulder surgery
- What this could lead to
- If the lower dose works as well for pain, it could reduce breathing problems and side effects after shoulder surgery while using less medication.
- What could go wrong
- This is a small, early-stage trial, and the lower dose might not control pain as effectively. Nerve blocks also carry risks like nerve injury or allergic reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 years or older. * ASA classification I-III. * Arthroscopic shoulder rotator cuff repair, capsular plication, acromioplasty, synovectomy, etc. Exclusion Criteria: * Have a history of lung disease. * Coagulation dysfunction or coagulopathy. * History of allergy to local anesthetics. * infection or lesions at the block site; or history of cervical spine disease. * pregnancy. * Refusal to participate in the study or inability to communicate. * Long-term use of opioids. * Body mass index \>35 kg/m2 * Previous history of nerve injury, paralysis, or paresis;
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Jiaxing University Affiliated Hospital
Jiaxing, Zhejiang, 314000, China