Can a vitamin a drug or light boost nail fungus cure?
NCT ID NCT06485505
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding low dose isotretinoin (a vitamin A drug) or excimer light to standard itraconazole pills works better for nail fungus. 36 adults with onychomycosis will be split into three groups: itraconazole alone, itraconazole plus isotretinoin, or itraconazole plus excimer light sessions. The goal is to see which combination improves nail appearance and clears the fungus.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- isotretinoin, excimer light, itraconazole
- What this could lead to
- If successful, this could point toward faster or more effective treatment for stubborn nail fungus by adding a second therapy.
- What could go wrong
- This is a very early Phase 1 trial with only 36 people, so results may not apply widely. Side effects from isotretinoin or light therapy are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Zagazig University Hospitals
RECRUITINGZagazig, Zagazig, 44519, Egypt
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