Can a vitamin a drug or light boost nail fungus cure?
NCT ID NCT06485505
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding low dose isotretinoin (a vitamin A drug) or excimer light to standard itraconazole pills works better for nail fungus. 36 adults with onychomycosis will be split into three groups: itraconazole alone, itraconazole plus isotretinoin, or itraconazole plus excimer light sessions. The goal is to see which combination improves nail appearance and clears the fungus.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
isotretinoin, excimer light, itraconazole
What this could lead to
If successful, this could point toward faster or more effective treatment for stubborn nail fungus by adding a second therapy.
What could go wrong
This is a very early Phase 1 trial with only 36 people, so results may not apply widely. Side effects from isotretinoin or light therapy are possible.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ONYCHOMYCOSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Zagazig University Hospitals
RECRUITINGZagazig, Zagazig, 44519, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••