Low-carb diet may help type 1 diabetes patients keep making some insulin

NCT ID NCT05536232

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study tests whether a low-carbohydrate diet (under 75 grams per day) can help adults with type 1 diabetes preserve their remaining insulin production. The idea is that the diet might calm the immune attack on insulin-making cells. Participants will follow the diet for a period while researchers measure insulin levels, blood sugar control, and immune markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
low carbohydrate diet (under 75 g per day)
What this could lead to
If it works, this could point toward a way to preserve some natural insulin production in type 1 diabetes, potentially reducing the amount of insulin needed.
What could go wrong
This is a small, early study with only 30 participants. The diet carries a risk of ketoacidosis, and it is not yet known whether any immune benefits will be seen.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-HP - Pitié-Salpêtrière Hospital

    Paris, 75013, France

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