New combo therapy aims to control advanced lung cancer in ALK-positive patients

NCT ID NCT07415005

First seen Feb 17, 2026 · Last updated May 08, 2026 · Updated 14 times

Summary

This phase 2 study tests whether combining the targeted drug lorlatinib with local treatments (like radiation or surgery) can better control advanced ALK-positive non-small cell lung cancer. About 30 people who have not had prior targeted therapy will take lorlatinib for 12 weeks, then may receive local therapy. The main goal is to check safety and side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas M. D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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