New drug trial targets resistant lung cancer

NCT ID NCT04621188

Summary

This study is testing whether the drug lorlatinib can help control advanced lung cancer with a specific genetic change (ROS1-positive) after the first targeted treatment has stopped working. It will involve about 54 adults whose cancer has continued to grow despite prior therapy. The main goal is to see if lorlatinib can shrink tumors and control the disease, including any that may have spread to the brain.

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Contacts and locations

Locations

  • AP-HP Hopital Tenon - Pneumologie

    Paris, 75020, France

  • AP-HP Hôpital Ambroise Paré

    Boulogne, 92104, France

  • AP-HP Hôpital Cochin

    Paris, 75014, France

  • Angers - CHU

    Angers, France

  • Annecy - CH

    Annecy, France

  • Antony - Hôpital privé

    Antony, France

  • Avignon - CH

    Avignon, France

  • Bordeaux - CHU

    Bordeaux, France

  • Bordeaux - Institut Bergonie

    Bordeaux, France

  • Bordeaux - Polyclinique

    Bordeaux, France

  • CHRU Grenoble

    Grenoble, France

  • CHU Bretonneau

    Tours, 37044, France

  • CHU Toulouse - Pneumologie

    Toulouse, France

  • Caen - CHU Côte de Nacre

    Caen, 14000, France

  • Centre Hospitalier - Pneumologie

    Le Mans, 72000, France

  • Centre Hospitalier Intercommunal de Créteil

    Créteil, 94000, France

  • Centre Hospitalier de la Côte Basque

    Bayonne, 64100, France

  • Centre Hospitalier du Pays d'Aix

    Aix-en-Provence, 13616, France

  • Centre Léon Bérard

    Lyon, 69373, France

  • Centre Paul Papin

    Angers, 49055, France

  • Chauny - CH

    Chauny, France

  • Cholet - CH

    Cholet, France

  • Clermont-Ferrand - CHU

    Clermont-Ferrand, France

  • Colmar - CH

    Colmar, France

  • Dijon - CRLCC

    Dijon, France

  • GRH Mulhouse Sud-Alsace

    Mulhouse, France

  • Hôpital Calmette

    Lille, 59037, France

  • Hôpital Foch

    Suresnes, 92151, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

  • Lyon - URCOT

    Pierre-Bénite, France

  • Nouvel Hôpital Civil - Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

  • Rouen - CHU

    Rouen, France

  • Valenciennes - Clinique

    Valenciennes, France

  • Vandoeuvre-lès-Nancy - CHU

    Vandœuvre-lès-Nancy, France

Conditions

Explore the condition pages connected to this study.