Two-year safety check for SMA drug in hundreds of patients

NCT ID NCT05232929

Summary

This study follows 404 adults and children with spinal muscular atrophy (SMA) who are already taking the approved drug risdiplam (Evrysdi). Researchers will track patients for about two years to monitor the long-term safety of the medication and see how well it continues to work. The goal is to gather more real-world information on the drug's effects over time.

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Contacts and locations

Locations

  • Advent Health Orlando

    Winter Park, Florida, 32789, United States

  • All Children's Research Institute, Inc.

    St. Petersburg, Florida, 33701, United States

  • Barrow Neurological Institute

    Phoenix, Arizona, 85013, United States

  • Central Texas Neurology Consultants

    Round Rock, Texas, 78681, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90010, United States

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Childrens Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Childrens Hospital of Wisconsin

    Milwaukee, Wisconsin, 53201, United States

  • Cincinnati Childrens Hospital

    Cincinnati, Ohio, 45229, United States

  • Columbia University Med Center

    New York, New York, 10032, United States

  • Gillette Children's Specialty Healthcare

    Minnetonka, Minnesota, 55343, United States

  • Helen DeVos Children's Hospital at Spectrum Health

    Grand Rapids, Michigan, 49503, United States

  • Instituto de Rehabilitación del Caribe

    Santurce, 00912, Puerto Rico

  • Loma Linda University Health Care

    Loma Linda, California, 92354, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medstar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Methodist Children's Hospital of South Texas

    San Antonio, Texas, 78229, United States

  • MultiCare Health System Institute for Research and Innovation

    Tacoma, Washington, 98405, United States

  • NYU Hospital for Joint Diseases

    New York, New York, 10003, United States

  • Nemour's Children's Hospital, Florida

    Orlando, Florida, 32827, United States

  • Neurology & Neuromuscular Care Center

    Denton, Texas, 76208, United States

  • Norton Children's Hospital

    Louisville, Kentucky, 40202, United States

  • Penn State Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • Rare Disease Research, LLC

    Atlanta, Georgia, 30329, United States

  • UBC (Remote Coordinating Center, no physical facility)

    Morgantown, West Virginia, 26508, United States

  • University California - Irvine

    Orange, California, 92868, United States

  • University Of Utah

    Salt Lake City, Utah, 84108, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72103, United States

  • University of California Davis Medical Center

    Sacramento, California, 95817, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Kentucky Medical Center

    Lexington, Kentucky, 40536, United States

  • University of Michigan Pediatric Rehabilitation Center

    Ann Arbor, Michigan, 48109, United States

  • University of Texas at Austin Health sciences, Dell Medical School

    Austin, Texas, 78723, United States

  • University of Virginia Children?s Hospital

    Charlottesville, Virginia, 22903, United States

  • Valley Children's Hospital

    Madera, California, 93636, United States

  • Washington University;Wash Uni. Sch. Of Med

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.