Hope for dravet syndrome: Long-Term safety trial of STK-001 underway

NCT ID NCT04740476

Ongoing Disease control Sponsor: Stoke Therapeutics, Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the long-term safety of an experimental drug called zorevunersen (STK-001) in 60 people with Dravet syndrome, a severe form of epilepsy. Participants must have completed an earlier STK-001 study. Researchers will monitor side effects, seizure frequency, and quality of life over time.

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Conditions

The condition(s) this trial relates to.

Dravet syndrome Epilepsies, Myoclonic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRAVET SYNDROME

Contacts and locations

Locations

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, 60611, United States
Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
Children's National Medical Center

Washington D.C., District of Columbia, 20010, United States
Cook Children's Medical Center

Fort Worth, Texas, 76104, United States
Florida Hospital for Children

Orlando, Florida, 32803, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Michigan Medicine

Ann Arbor, Michigan, 48109, United States
MultiCare Health System Institute for Research and Innovation

Tacoma, Washington, 98405, United States
NYU Comprehensive Epilepsy Center

New York, New York, 10016, United States
Nicklaus Children's Hospital

Miami, Florida, 33155, United States
Oregon Health & Science University

Portland, Oregon, 97239, United States
Seattle Children's Hospital

Seattle, Washington, 98105, United States
UT LeBonheur Pediatric Specialists, Inc.

Memphis, Tennessee, 38103, United States
University of California San Francisco Medical Center

San Francisco, California, 94158, United States
University of Iowa Children's Hospital

Iowa City, Iowa, 52242, United States

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