Gene therapy safety check: researchers track hepatitis b patients years after treatment

NCT ID NCT07254208

First seen Dec 08, 2025 · Last updated Apr 28, 2026 · Updated 14 times

Summary

This study follows 45 people with chronic hepatitis B who have already received the experimental gene therapy PBGENE-HBV in an earlier trial. Researchers will monitor them for delayed side effects over time. No new treatment is given; the goal is to understand the long-term safety of the gene editing product.

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Contacts and locations

Locations

  • ICS ARENSIA Exploratory Medicine SRL

    Chisinau, Moldova, 2025, Moldova

  • Massachusetts General Hospital/Harvard University

    Boston, Massachusetts, 02114, United States

  • New Zealand Clinical Research

    Auckland, New Zealand, 1010, New Zealand

  • Queen Mary Hospital, University of Hong Kong

    Hong Kong, Hong Kong, Hong Kong

Conditions

Explore the condition pages connected to this study.