Sickle cell drug pociredir tested for Long-Term safety in 50 patients

NCT ID NCT07401823

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the long-term safety of the drug pociredir in 50 adults with sickle cell disease who have already taken it and seen benefits in an earlier study. Participants will take pociredir once daily for up to 48 months. The main goal is to track side effects and other health changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pociredir (also called FTX-6058)

What this could lead to

If successful, this could show that pociredir is safe enough to use long-term for managing sickle cell disease, potentially reducing complications.

What could go wrong

This is a small, early-phase extension study with no comparison group, so results may not prove effectiveness. Long-term side effects are still unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

beta thalassemia hematologic disorder sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • Jacobi Medical Center

    The Bronx, New York, 10461, United States

  • Our Lady of the Lake Hospital

    Baton Rouge, Louisiana, 70808, United States

  • Queens Hospital Cancer Center

    Jamaica, New York, 11432, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

  • University of Texas Houston

    Houston, Texas, 77030, United States