Extended safety check for liver disease drug shows ongoing monitoring for rare conditions

NCT ID NCT04168385

Summary

This study monitored the long-term safety of maralixibat, a medication for rare cholestatic liver diseases like Alagille Syndrome. It included 52 patients who had already taken the drug in previous clinical trials and continued treatment. Researchers tracked side effects and looked at long-term effects on itching and bile acid levels.

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Contacts and locations

Locations

  • Baylor College of Medicine/Texas Children's Hospital

    Houston, Texas, 77030, United States

  • Birmingham Children's Hospital

    Birmingham, United Kingdom

  • Children Hospital of Pittsburgh

    Pittsburgh, Pennsylvania, 15224, United States

  • Children'S Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital Westmead

    Westmead, New South Wales, 2145, Australia

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cliniques Universitaires Saint-Luc

    Brussels, Belgium

  • Hopital Kremlin Bicetre

    Paris, 94275, France

  • Hopital Necker-Enfants Malades

    Paris, 75015, France

  • Hospital Universitario La Paz- Hospital Materno Infantil

    Madrid, 261, Spain

  • Hospital for Sick Children

    Toronto, Canada

  • Leeds Teaching Hospital NHS Trust

    Leeds, LS1 3EX, United Kingdom

  • Paediatric Liver Center, Kings College Hospital

    London, SE5 9RS, United Kingdom

  • Riley Hospital For Children

    Indianapolis, Indiana, 46202, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • The Children's Memorial Health Institute

    Warsaw, 04-730, Poland

  • The Royal Children'S Hospital Melbourne

    Parkville, Victoria, 3052, Australia

Conditions

Explore the condition pages connected to this study.