Gene therapy for ear tumors: Long-Term safety under review
NCT ID NCT07503613
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 100 people with vestibular schwannoma (a non-cancerous ear tumor) who previously received a gene therapy called AAVAnc80-antiVEGF. Researchers will monitor for late side effects and measure tumor size changes over time using MRI scans. The goal is to understand the long-term safety and whether the therapy keeps working.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AAVAnc80-antiVEGF gene therapy
What this could lead to
If successful, this could show that a single gene therapy injection safely controls tumor growth and reduces the need for repeated treatments.
What could go wrong
This is an observational follow-up study, not a new treatment test. It may reveal long-term risks like new tumors or immune problems, and results may not apply to everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Texas Southwestern
Dallas, Texas, 75390, United States