Promising POTS drug study halted early – what we know

NCT ID NCT05918978

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study looked at the long-term safety of a drug called efgartigimod for adults with post-COVID postural orthostatic tachycardia syndrome (POTS), a condition that causes dizziness and rapid heartbeat when standing. It enrolled 33 people who had completed a previous study. The trial was terminated early, but the data collected may still provide insights into how the drug works and its side effects.

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Contacts and locations

Locations

  • Apex Trials Group

    Fort Worth, Texas, 76104, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • Metrodora Institute

    West Valley City, Utah, 84119, United States

  • North Shore University HealthSystem

    Glenview, Illinois, 60026, United States

  • Pioneer Clinical Research

    Rosharon, Texas, 77583, United States

  • Standford Movement Disorder Center

    Palo Alto, California, 94304, United States

  • UC Sand Diego Sulpizio Cardiovascular Center

    La Jolla, California, 92037, United States

  • University Hospitals, Neurology Clinical Trials

    Cleveland, Ohio, 44106, United States

Conditions

Explore the condition pages connected to this study.